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Submited on: 10 Apr 2012 03:21:05 AM GMT
Published on: 10 Apr 2012 05:42:19 PM GMT
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Other Comments:
This is a good paper that adds further information on the biological behaviour of prostate cancer,
in that patients with high PSA, high grade,high tumour category have a greater risk of developing PSA FAILURE after radical prostatectomy for localised prostate cancer.
By the same token the individual parameters of PSA,GLEASON SCORE and TUMOUR CATEGORY are not sufficient to completely distinguish between those patients who will develop PSA failure after radical prostatectomy.
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Competing interests:
no
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Invited by the author to review this article? :
No -
Have you previously published on this or a similar topic?:
No
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References:
None -
Experience and credentials in the specific area of science:
I have been involved in the management of prostate cancer for more than 20 years
- How to cite: Odey J O.serum PSA, Gleason Score andclinical staging in predicting biochemical(PSA) FAILURE AFTER RADICAL PROSTATECTOMY FOR CARCINOMA OF PROSTATE[Review of the article 'Serum PSA, Gleason Score and Clinical Staging in Predicting Biochemical (PSA) Failure After Radical Prostatectomy for Carcinoma of Prostate ' by Barnes D].WebmedCentral 2012;3(5):WMCRW001795
- Other Comments: 3. Original but not new contribution 5. The whole text could be shorter without loosing any information 6. Under the Materials and Methods section, the sub-sections on Data collection and Analysis of results can be abridged without any loss of information.
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Competing interests:
None
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Invited by the author to review this article? :
No -
Have you previously published on this or a similar topic?:
Yes
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References:
Eke, N and Essiet, A. Cancer of the prostate gland: So much verbiage, so little mileage. Journal of the West African college of surgeons. Jan-Mar 2011; 1: 2-30. -
Experience and credentials in the specific area of science:
Practicing urologist in a university hospital setting, with over 15 years experience in the care of prostate cancer patients - How to cite: Essiet A .Review of pre-op PSA, Gleason score and Clinical stage of disease in predicting biochemical recurrence post radical prostatectomy for prostate cancer.[Review of the article 'Serum PSA, Gleason Score and Clinical Staging in Predicting Biochemical (PSA) Failure After Radical Prostatectomy for Carcinoma of Prostate ' by Barnes D].WebmedCentral 2012;3(4):WMCRW001757
predicting factors for biochemical recurrence post radical prostatectomy
very important but very standard, the paper adds nothing
no, nothing new
yes
the authors couldn't reach good conclusion, due to the small number of cases.
not applicable
poor analysis due to small number of cases
if the authors would have prostate tissues, may be some immunohistochemical staining would add to their work.
no, it adds nothings
authors are great, they like to do good job. but; in writing about things that are well settled in literatures and textbooks, they need to look for a small point that is new or even study the same parameters as they did but on a larger cohort of patients.
no
No
Yes
Ahmed Kotb, Ahmed Elabbady. Prognostic factors for the development of biochemical recurrence after radical prostatectomy. Prostate cancer 2011; 2011: 485189. Ahmed Kotb, Simon Tanguay, Murilo Luz, Wassim Kassouf, Armen Aprikian. Relationship between initial PSA density with future PSA kinetics and repeat biopsies in men with prostate cancer on active surveillance. Prostate cancer and prostatic diseases Journal 2011 Mar; 14(1): 53- 7.
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