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WebmedCentral Immunology
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Occurrence of Stromal Derived Factor-1 Polymorphism In Kenyan Population
Abstract: Genetic polymorphism in chemokine receptors and coreceptor genes influences susceptibility to HIV-1 infection and disease progression. The mutated Stromal Derived Factor-1 3A`/3A` (SDF-1 3’A) competes with the virus for the coreceptor site Cystein-X-cystein receptor 4 (CXCR4) on the CD4+ T-cells therefore down-regula..
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Relationship between the T-cell Diversity and the Defence Polymorphism among Classical Populational Morphs and their Interbreeding Town-village Hybrid Offspring
Abstract: The problem of creating an easy, quick, field, mass screening, in vivo discrimination test is still on the agenda. We believe that such potential has the phytohemagglutinin- histamin (PHA-H) intradermal method of Zhukov et al. (1984). This method reveals not only the normal immunomodulatotor (Th/Ts) index (NIMI) and Th..
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Immune Response of IL-4-Knockout Mice to Low-Dose Immunization with Autologous IL-4
Abstract: The immune response in IL-4-knockout mice to murine interleukin-4 (IL-4) at immunization doses in range of 1-10 μg was evaluated. Different adjuvants, anti-IL-4 carrier antibodies, and cross-activation monoclonal antibodies were used in immunization protocols. Antibody titers were measured by enzyme-linked immunosorbe..
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Immune Response of IL-4-Knockout Mice to Low-Dose Immunization with Autologous IL-4
Abstract: The immune response in IL-4-knockout mice to murine interleukin-4 (IL-4) at immunization doses in range of 1-10 μg was evaluated. Different adjuvants, anti-IL-4 carrier antibodies, and cross-activation monoclonal antibodies were used in immunization protocols. Antibody titers were measured by enzyme-linked immunosorbe..
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Lessons from Immunogenetics Unfold Inherent Demographic Health Issues
Abstract: The human population is diverse and adapted to all sorts of lifestyles in the tropical, subtropical and temperate zones. This is made possible not only due to food habits but also due to the tolerance and molecular acquaintances with the microbial world around us. In consequence, the species Homo sapiens is bestowed wi..
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Immuno-prophylaxis against development of cardiac valvular complications in patients with rheumatic fever: A proposed method
Abstract : Rheumatic heart disease (RHD) is a serious medical condition recognized as an immunologically mediated complication of rheumatic fever with an autoimmune component due to molecular mimicry between the bacterial antigens and certain body tissues. In view of the prevalence and seriousness of the disorder, its prophylaxis..
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A Possible Mechanism of Abrogating Progression of Web Beyond Anti-Idiotypic Antibody and a Non Traditional Pathway of Complement Activation
Abstract: The progression of immune response is currently believed to give rise to anti-anti-idiotypic antibodies. This new hypothesis offers an explanation for the termination or abrogation of potentially endless progression of immune response after the elimination of antigen from the system...
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Psychoneuro Immunology (p.n.i) Of Stress
Abstract: Considerable evidence demonstrating a relationship between stress and immune function is accumulating and a complex chain of biologic and psychologic processes are involved. An extensive network of central nervous system and endocrine system processes may be involved in the modulation of the immune system in response t..
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Correlation Between Intestinal Protozoan Infection and Diarrhea in HIV/AIDS Patients
Abstract: From May to December, 2006, stool samples from 900 patients attending four hospitals in Abuja, Nigeria were collected and examined for the presence of intestinal protozoan. The aim of the study was to determine if correlation exists between intestinal protozoan infection and diarrhea in HIV/AIDS patients. Of the 900 in..
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The Natural Killer Cell - 'Missing-Self' Recognition Strategy
Abstract : The immune system is a built-in defense mechanism, which continuously monitors invading pathogens in all living organisms and keeps them physiologically fit. Both the innate and adaptive arms of the immune system are involved in this process of tolerating ‘self’ and targeting ‘non-self’ cells and their respecti..
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- Toll-like Receptors (TLRs) and Prion Disease: Relevance to Pathology and Novel T... on 03rd Nov 2017
- Lessons from Immunogenetics Unfold Inherent Demographic Health Issues ... on 14th Feb 2014
- Occurrence of Stromal Derived Factor-1 Polymorphism In Kenyan Population ... on 25th Jul 2012
- Relationship between the T-cell Diversity and the Defence Polymorphism among Cla... on 16th May 2012
- Occurrence of Stromal Derived Factor-1 Polymorphism In Kenyan Population ... on 29th Apr 2012
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