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WebmedCentral Bioinformatics
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A short note on comparative analysis of acetylcholinesterase genes in mosquito genome
Abstract: Acetylcholineserase genes confer the organophosphate and carbamate resistance mechanism. A total of 46 acetylcholineserase genes in the 24 mosquito genomes were identified. In this study, all the analysed mosquito genomes have the two acetylcholinesterase genes (ace-1 and ace-2) except Aedes albopictus and Anopheles si..
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The Glycoprotein Mucin-Like Domain (MLD) in the Zaire ebolavirus (EBOV) may be responsible for the manifestations of Post-Ebola Virus Disease Syndrome (PEVDS)
Abstract: The incidence of various ocular, CNS, and musculoskeletal complaints in the convalescent period following recovery from Ebola Virus Disease (PEVDS) has become an intense area of interest in the aftermath of the recent West Africa outbreak 2014-2015. A review of past outbreaks involving EBOV, SUDV, TAFV, and BDBV reveal..
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In Silico Identification of Rice Gene Homologues in Brachypodium, Sorghum and Maize: Insight into Development of Gene Specific Markers
Abstract: Rice, one of the important cereal species, is considered as a model for studying grass family. Whole rice genome is recently sequenced, fully annotated and hundreds of genes are characterized. Molecular resources in rice are ever increasing since the draft became publicly available and the information is being utilized..
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In Silico Identification of Rice Gene Homologues in Brachypodium, Sorghum and Maize: Insight into Development of Gene Specific Markers
Abstract: Rice, one of the important cereal species, is considered as a model for studying grass family. Whole rice genome is recently sequenced, fully annotated and hundreds of genes are characterized. Molecular resources in rice are ever increasing since the draft became publicly available and the information can be utilized t..
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Homology Modeling and Docking Studies Showed that Dihydrofolate Reductase from Pseudomonas Putida is a Possible Choice for Diagnosis of Serum Trimethoprim by Enzyme Inhibiton Assay
Abstract: Trimethoprim is a chemotherapeutic drug mainly used in prophylaxis and treatment of bacterial infections. It belongs to dihydrofolate reducase inhibitors and has bacteriostatic properties. It may cause serious side effects if it is overdosed or used for long time. It may cause renal clearance mechanism impairment, thro..
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An Efficient Pharmacophore Generation Strategy To Identify New Leukotriene A4 Hydrolase (lta4h)
Abstract: Leukotriene A4 Hydrolase as a potent inhibitor in inflammation. Leukotriene A4 hydrolase, also known as LTA4H is a human gene. The protein encoded by this gene, a bifunctional zinc enzyme converts leukotriene A4 to leukotriene B4 (LTB4). Arachidonic acid is a polyunsaturated fatty acid that is present in the phospholip..
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Evaluation of neural network performance in the protein secondary structure prediction problem
Abstract: In the context of the protein secondary structure prediction problem, we examine the performance of various neural network architectures commonly applied in the literature. Specifically,by applying the neural network paradigm, mappings between training vectors and their desired targets are constructed. The class member..
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Cross Platform In Silico Design And Evaluation Of Small Interfering Rnas That Target The Expression Of Plasmodium Falciparum Heat Shock Protein 90 (pfhsp90) Gene
Abstract : It has been shown that it is both efficient and cost effective to run experiments in silico before actual laboratory work in real time. Plasmodium falciparum heat shock protein 90(pfHsp90) appears sufficiently different from the human type to serve as an appropriate drug target. This expectation will need to be evaluat..
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RNA Structures Affected By Single Nucleotide Polymorphisms In Transcribed Regions Of The Human Genome
Abstract: Single-stranded RNAs fold into base-paired structures sometimes critical for RNA function.We report the first genome-wide computational analysis of mRNA structures, obtaining predicted minimum free energy structures (MFE) and ensembles of top-scoring structures.Evaluation of mRNA structures from >12,450 genes indicates..
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In Silico Techniques for the Identification of Novel Natural Compounds for Secreting Human Breast Milk
Abstract: Low milk supply is an abounding problem endured by the pregnant women in every country. Many of them consume herbs and vegetables to stimulate the secretion of the breast milk. Some of the commercially available drugs that are used for the purpose are domperidone, metachlopromide (reglan) and many more. The main object..
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- Latest ReviewsView all
- Homology Modeling and Docking Studies Showed that Dihydrofolate Reductase from P... on 01st Nov 2017
- The Glycoprotein Mucin-Like Domain (MLD) in the Zaire ebolavirus (EBOV) may be r... on 29th Feb 2016
- The Glycoprotein Mucin-Like Domain (MLD) in the Zaire ebolavirus (EBOV) may be r... on 02nd Feb 2016
- In Silico Identification of Rice Gene Homologues in Brachypodium, Sorghum and Ma... on 30th Jul 2012
- In Silico Identification of Rice Gene Homologues in Brachypodium, Sorghum and Ma... on 10th Jul 2012
- Latest CommentsView all
- Note added in proof .. Posted on RNA Structures Affected By Single Nucl...
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