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Dr. Alain Thierry

INSERM
UMR 3145
CAP DELTA 1682 Rue de la Valsière
 

Brief Biography:


Dr. Alain .R. Thierry is Chargé de Recherche 1° classe of the INSERM affiliated to the Sysdiag UMR 3145 laboratory (Modélisation et Ingénierie des systèmes biologiques pour le diagnostic), Montpellier II (France). He has a strong experience in cancer therapy and drug delivery being the principal investigator of breakthrough findings such as (i) the circumvention of multi-drug resistance in tumors through drug delivery ; (ii) the encapsulation of an anti-cancer agent using pre-formed liposomes which is under second phase clinical trial with NeoPharm, IL, and Pharmacia-Upjohn, USA ; (iii) the DLS or Neutraplex system, as one of the most potent nucleic acids delivery system for systemic administration; and recently (iv), the general supramolecular auto organization of DNA as a complex system. His work led to a publication record in high quality journals, his requested presence as a speaker at international meetings in the field, as well as current and pending patents. Following two years as post-doc at the INSERM U71, Alain Thierry spent seven years in the United States, as Postdoctoral fellow and Adjunct Assistant Professor at the Georgetown University School of Medicine, Lombardi Cancer Center, (Washington, DC) and Visiting Scientist at the National Cancer Institute (Bethesda, MD; LTCB/NCI/NIH, Dr R.C. Gallo, Chief). He has been a Research Scientist at the company Transgene (Strasbourg, France). He was at Biovector Therapeutics (Labège, France) Director of the Gene Therapy Program from 1997 to 2000. He is Guest Researcher at the Institute of Human Virology (Dr R.C. Gallo, chief; Baltimore, USA) from September 2000 Dr. A.R. Thierry created in January 2003 the biotech company MedinCell SA (Montpellier, France). He was Chief of Science Officer of this company.  He was Associate Professor at the University of Montpellier II from 2001 to 2007.

Dr. A.R. Thierry’s former main research interests and expertise on auto-assembling system involving DNA condensation and on the development of nanotechnologies for nucleic acids delivery  beneficiate, now, to a novel program on the structure and biology of circulating DNA during cancer progression and use as a diagnostic/theranostic tool in oncology.

 

Academic positions:


Senior Investigator at the National Institute of Health and Medical Research, INSERM, France

Pedagogic consultant at the University of Sciences Montpellier 2

 

Research interests:


Expertise in auto-assembling system involving DNA condensation and on the development of nanotechnologies for nucleic acids delivery  that will beneficiate, now, to a novel program on the structure and biology of circulating DNA during cancer progression and use as a diagnostic/theranostic tool in oncology.

 

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