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Dr. Vittorio Gentile

Researcher
Dept. Biochemistry and Biophysics, Second University of Naples
via Costantinopoli 16
 

Brief Biography:


DATE AND PLACE OF BIRTH :

July 06, 1960; Torre del Greco, Naples, Italy.

 

CITIZENSHIP:

Italian.

                       

LANGUAGES:

Italian, English, French.

 

 

EDUCATION:

1978-1984: -M.D., 1st Medical School, University of Naples with Summa cum Laude. Thesis: "The role  of polyamines in MSO-induced seizures".

1984-1991: -Speciality Diploma, 1st Medical School, University of Naples; Neurology Program.

1986-1990: -Ph.D. in Biochemical Sciences, 1st Medical School, University of Naples and Bari. Thesis: "Cloning, characterisation and stable expression in Balb-c 3T3 cells of the human tissue transglutaminase cDNA from endothelial cells".

 

 

Academic positions:


1980-1984: -Internship at the Department of Biochemistry and Biophysics, University of Naples.

1984-1985: -Post-Doctoral Fellow at the same institution.

1986: -Fellow at the Laboratorio di Tossicologia Comparata ed Ecotossicologia, Istituto Superiore di Sanità, Roma, Italy.

1987-1988: -Fellow at the Department of Biochemistry and Biophysics, University of Naples.

1988-1991: -Fellow at the Department of Pharmacology, University of Texas-Medical School, Houston.

1991: -Scientific consultant for Fidia Inc., Abano Terme.

1992-1993: -Visiting Assistant Professor at the Department of Pharmacology, University of Texas-Medical School at Houston.

1991-2005: -Research Assistant Professor at the Department of Biochemistry and Biophysics, II University of Naples.

 

2005-to date: Aggregate Professor of Biochemistry at the Department of Biochemistry and Biophysics, II University of Naples.

 

Research interests:


-Studies on cerebral polyamine metabolism.

 

-Studies on polyamine binding to synaptosomal membranes of rat brain.

 

-Characterisation of rat intestinal transglutaminase and studies on transglutaminase-mediated modifications of gliadins in relation to the Coeliac Disease.

 

-Cloning and characterisation of the gene for human tissue transglutaminase.

 

-Transfection of the human tissue transglutaminase cDNA in Balb-C 3T3 mouse fibroblasts: molecular and cellular characterisation of the stable transfected cell lines.

 

-Site direct mutagenesis of the human tissue transglutaminase cDNA.

 

-Characterization of the human tissue transglutaminase as a mediator of the cell signal transduction pathway.

 

-Studies on the possible involvement of tissue transglutaminase in pathogenesis of CAG triplet diseases.

 

 

What I think of the idea behind WebmedCentral:


Very good project