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Prof. Henry Young

Full Professor of Anatomy
Mercer Univesity School of Meddicine
1550 College St., Macon, Georgia
 

Brief Biography:


HIGHER EDUCATION:

Ohio State University, Columbus, OH - B.S., Biology, 1974

University of Arkansas, Fayetteville, AR - M.S., Zoology, 1977 Master's Thesis: Limb Regeneration in the Adult Salamander, Ambystoma annulatum Cope 1889 (Amphibia: Ambystomatidae). (Dr. Claudia F. Bailey, mentor)

Texas Tech University, Lubbock, TX - Ph.D., Anatomy, 1983Ph.D. Thesis: A Temporal Examination of Glycoconjugates During the InitiationPhase of Limb Regeneration in Adult Ambystoma. (Dr. Roger R. Markwald, mentor)

Case Western Reserve University, Cleveland, OH - Postdoctoral Fellow, Carbohydrate Biochemistry (Dr. Arnold I. Caplan, mentor), 1983-1987

Rush Presbyterian St. Luk's Medical Center, Chicago, IL - Instructor of Biochemistry, Hybridoma technology (DR. James Kimura, mentor), 1987-1988

Discovered: Anti-Scarring Agent, Skeletal Muscle Morphogenetic Protein, and cloned from single cells: Adult germ layer lineage mesodermal stem cells (GL-MesoSCs), Adult pluripotent epiblast-like stem cells (ELSCs), Adult totipotent blastomere-like stem cells (BLSCs).

 

Academic positions:


1988-1995: Assistant Professor of Anatomy, Division of Basic Medical Science, Mercer University School of Medicine, Macon, GA (MUSM).

1988-Pres: Director of Embryology, Division of Basic Medical Science, MUSM.

1988-1993: Co-Director of Histology, Division of Basic Medical Science, MUSM.

1988-1994: Adjunct Assistant Professor of Surgery, Department of Surgery, MUSM.

1988-1989: Interim Director of Surgical Research, Department of Surgery, MUSM.

1989-1994: Assistant Director of Surgical Research, Department of Surgery, MUSM.

1995-2004: Associate Professor of Anatomy, with Tenure, Division of Basic Medical Science, MUSM.

1995-2004: Adjunct Associate Professor of Pediatrics, Department of Pediatrics, MUSM.

1995-2008: Co-Director of Gross Anatomy, Division of Basic Medical Science, MUSM.

2004-Pres: Full Professor of Anatomy, with Tenure, Division of Basic Medical Science, MUSM.

2004-Pres: Adjunct Full Professor of Pediatrics, Department of Pediatrics, MUSM.

2005-2010: Co-Director of Cell Biology, Embryology, Histology, and Gross Anatomy for MSA611 Certified Registered Nurse Anesthesiology Program

2008-Pres: Adjunct Full Professor of Obstetrics & Gynecology, Department of Obstetrics & Gynecology, MUSM

2008-2010: Director of Gross Anatomy, Division of Basic Medical Science, MUSM

2008-Pres:  Professor of Anesthesiology, Department of Anesthesiology, MUSM

2008-2010: Director of Anatomy: Cell Biology, Embryology, Histology, Neuroanatomy, and Gross Anatomy for MSA611 Certified Registered Nurse Anesthesiology Program

2008-2010: Director, Anatomy for Surgeons, MAS.B01, MUSM MS IV Elective Clerkship Program.

 

Research interests:


His research interests began in his Master's program and centered on the role of endogenous stem cells and factors that control their response during tissue repair and tissue regeneration. His Master's and Ph.D. research encompassed limb regeneration in adult terrestrial salamanders. This is where he made his initial discovery in 1975. Adult regenerating salamander limb blastema was composed of activated, previously quiescent, stem cells as well as factors that controlled their differentiation. Since joining Mercer's faculty he discovered, and was the first to clone from a single cell, adult-derived germ layer lineage mesodermal stem cells (GL-MesoSCs, a single cell that can form any cell of mesodermal origin). Next, he discovered, and was the first to clone from a single cell, adult-derived pluripotent epiblastic-like stem cells (ELSCs, a single cell that can to form any somatic body cell of ectodermal, mesodermal, or endodermal origin). He next discovered, and was the first to clone from a single cell, an adult-derived totipotent blastomere-like (and by default, pluripotent) stem cell (BLSCs, a single cell that can form all somatic cells of the body, the gametes [sperm and ova], and the placenta). While skeletal muscle has been his "gold standard" for isolating these stem cells, his lab was recently able to isolate these same stem cells in fairly pure form circulating within the peripheral blood of 11 species of adult mammals, including humans. Thus far, he can isolate autologous and allogeneic adult stem cells [GLSCs, ELSCs, and BLSCs] from mouse, rat, rabbit, cat, dog, sheep, goat, pig, cow, horse, and human. His current research focuses on the capabilities of the adult-derived stem cells to facilitate tissue repair and tissue regeneration in humans and other mammals.

 

Any other information:


Prof. Young has consulted with many companies with respect to his research interests, i.e., the cells involved in tissue repair and healong and the factors that control their responses. The companies he has consulted with include Amgen, Genetics Institute, R&D, Genentech, Sigma-Aldrich, Cal BioChem, Advanced Tissue Sciences, MorphoGen Pharmaceuticals Inc., Cybios LLC, Moraga Biotechnology Corp., Athersys, Stem Cell Tech, Sea Change For Life, BioRegenesis Institute, Henry E. Young LLC, PluriGenesis, Adult Stem Cells Do It Better LLC, Adult Stem Cell Farms LLC, Adult Stem Cells Are Us, and Adult Stem Cells Forever.

Prof. Young spent the summer of 2011 helping to set up an adult autologous ?stem cell clinic in Henderson, Nevada. The aim of the clinic was to provide high quality low cost adult autologous stem cell therapy to people with somatic diseases, except cancer and obesity. Thus far they have successfully treated peole with COPD, neuropathic pain, sciatica, neuroparesthesias, multiple sclerosis, pulmonary fibrosis, alopecia, and cerebral palsy. In the mid fall of 2011 they will be treating Parkinson's patients under an approved IRB to test the use of audult autologous stem cells for the treatment of neurological disease. If this treatment is successful, this would open up treatment for Alzheimer's disease, dementia, epilepsy, and spinal cord regeneration. If the FDA allows allogeneic stem cell transplant as a form of gene therapy, this would exponentially open up treatments for any genetically-related disease process. These diseases include muscular dystrophy, myasthenia gravis, systemic lupus erythematosus, and other autoimmune diseases such as Hashimoto's disease, Type-I Diabetes Mellitus, Scleroderma, Rheumatoid Arthritis, etc.

 

What I think of the idea behind WebmedCentral:


I think it is an excellent idea.

 

Home Page:


http://medicine.mercer.edu/search?bio=young_he@mercer.edu&bio_num=0