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Prof. Gert Kostner

Professor Molecular Biology & Biochemistry
Medical University of Graz
Harrachgasse
 

Brief Biography:


http://forschung.meduni-graz.at/fodok/suchen.person_publikationen?sprache_in=en&ansicht_in=&menue_id_in=102&id_in=90075237&publikation_typ_id_in=&sortierung_in=sci

2011-Full papers/articles (Journal)

** Indumathi Chennamsetty1, Thierry Claudel2, Karam M. Kostner3, Anna Baghdasaryan2, Dagmar Kratky1, Sanja Levak-Frank1, Sasa Frank1, Frank J. Gonzalez4, Michael Trauner2,5 and Gert M. Kostner

Farnesoid X receptor represses hepatic human APOA gene expression

J Clin Invest.  doi:10.1172/JCI45277.

** Pfeifer, T; Buchebner, M; Chandak, PG; Patankar, J; Kratzer, A; Obrowsky, S; Rechberger, GN; Kadam, RS; Kompella, UB; Kostner, GM; Kratky, D; Levak-Frank, S Synthetic LXR Agonist Suppresses Endogenous Cholesterol Biosynthesis and Efficiently Lowers Plasma Cholesterol.

Curr Pharm Biotechnol. 2011; 12(2):285-292 PubMed

2010-Full papers/articles (Journal)

** Buchebner, M; Pfeifer, T; Rathke, N; Chandak, PG; Lass, A; Schreiber, R; Kratzer, A; Zimmermann, R; Sattler, W; Koefeler, H; Froehlich, E; Kostner, GM; Birner-Gruenberger, R; Chiang, KP; Haemmerle, G; Zechner, R; Levak-Frank, S; Cravatt, BF; Kratky, D Cholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363.

J Lipid Res. 2010; 51(10): 2896-2908. [OPEN ACCESS] PubMed PUBMED Central FullText FullText_MUG

Abstracts (Journal)

** Chennamsetty, I; Kostner, G ROLE OF FARNESOID X RECEPTOR AGONISTS IN THE IN VIVO AND IN VITRO EXPRESSION OF APOLIPOPROTEIN(a)

ATHEROSCLER SUPPL. 2010; 11(2): P210 [Poster]

** Porpaczy, EA; Tauber, S; Bilban, M; Kostner, G; Gruber, M; Le, T; Fleiss, K; Skrabs, C; Einberger, C; Shehata, M; Jaeger, U; Vanura, K Expression of Lipoprotein Lipase In Chronic Lymphocytic Leukemia Cells: Is There a Biological Function?

BLOOD. 2010; 116(21): 1474-1474.

** Porpaczy, EA; Tauber, S; Bilban, M; Kostner, G; Gruber, M; Le, T; Fleiss, K; Skrabs, C; Einberger, C; Shehata, M; Jaeger, U; Vanura, K C-Abl Regulates Mcl-1 Gene Expression In Chronic Lymphocytic Leukaemia Cells

BLOOD. 2010; 116(21): 1474-1474.

** Porpaczy, EA; Tauber, S; Bilban, M; Kostner, G; Gruber, M; Le, T; Fleiss, K; Skrabs, C; Emberger, C; Shehata, M; Jaeger, U; Vanura, K Expression of Lipoprotein Lipase In Chronic Lymphocytic Leukemia Cells Is There a Biological Function?

BLOOD. 2010; 116(21): 1474-1474.

2009-Full papers/articles (Journal)

** Graier, WF; Malli, R; Kostner, GM Mitochondrial protein phosphorylation: instigator or target of lipotoxicity?

Trends Endocrinol Metab. 2009; 20(4): 186-193. PubMed FullText FullText_MUG Google Scholar

** Kratzer, A; Buchebner, M; Pfeifer, T; Becker, TM; Uray, G; Miyazaki, M; Miyazaki-Anzai, S; Ebner, B; Chandak, PG; Kadam, RS; Calayir, E; Rathke, N; Ahammer, H; Radovic, B; Trauner, M; Hoefler, G; Kompella, UB; Fauler, G; Levi, M; Levak-Frank, S; Kostner, GM; Kratky, D Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia.

J Lipid Res. 2009; 50(2): 312-326. [OPEN ACCESS] PubMed PUBMED Central FullText FullText_MUG Google Scholar

** Sacks, FM; Rudel, LL; Conner, A; Akeefe, H; Kostner, G; Baki, T; Rothblat, G; de la Llera-Moya, M; Asztalos, B; Perlman, T; Zheng, CY; Alaupovic, P; Maltais, JAB; Brewer, HB Selective delipidation of plasma HDL enhances reverse cholesterol transport in vivo.

J Lipid Res. 2009; 50(5):894-907 [OPEN ACCESS] PubMed PUBMED Central FullText FullText_MUG Google Scholar

2008-Full papers/articles (Journal)

** Calayir, E; Becker, TM; Kratzer, A; Ebner, B; Panzenböck, U; Stefujl, J; Kostner, GM LXR-agonists regulate ApoM expression differentially in liver and intestine.

Curr Pharm Biotechnol. 2008; 9(6): 516-521. PubMed Google Scholar

2007-Full papers/articles (Journal)

** Friedl, G; Schmidt, H; Rehak, I; Kostner, G; Schauenstein, K; Windhager, R Undifferentiated human mesenchymal stem cells (hMSCs) are highly sensitive to mechanical strain: transcriptionally controlled early osteo-chondrogenic response in vitro.

Osteoarthritis Cartilage. 2007; 15(11):1293-1300 PubMed FullText FullText_MUG Google Scholar

** Widhalm, K; Dirisamer, A; Lindemayr, A; Kostner, G Diagnosis of families with familial hypercholesterolaemia and/or Apo B-100 defect by means of DNA analysis of LDL-receptor gene mutations.

J Inherit Metab Dis. 2007; 30(2):239-247 PubMed FullText FullText_MUG Google Scholar

Reviews

** Kostner, KM; Kostner, GM Fibrate in lipid metabolism disorders

Pharm Unserer Zeit. 2007; 36(2): 114-119. PubMed

Abstracts (Journal)

** Petlevski, R; Kostner, GM; Frank, S; Juretic, D; Kalogjera, Z Protective effect of the flavonoid myricetin on glucose induced oxidative stress in Hep G2 cells

PLANTA MED. 2007; 73(9):978-979. [Oral Communication]

2006-Full papers/articles (Journal)

** Idzior-Walus, B; Sieradzki, J; Kostner, G; Malecki, MT; Klupa, T; Wesolowska, T; Rostworowski, W; Hartwich, J; Walus, M; Kiec, AD; Naruszewicz, M Familial lecithin-cholesterol acyltransferase deficiency: biochemical characteristics and molecular analysis of a new LCAT mutation in a Polish family.

Atherosclerosis. 2006; 185(2):413-420 PubMed FullText FullText_MUG Google Scholar

** Koidl, J; Hödl, H; Schmid, MG; Konrad, M; Petschauer, S; Kostner, GM; Gübitz, G Chiral separation of T3 enantiomers using stereoselective antibodies as a selector in micro-HPLC.

J BIOCHEM BIOPHYS METH. 2006; 69(1-2): 33-42. PubMed FullText FullText_MUG Google Scholar

** Osibow, K; Malli, R; Kostner, GM; Graier, WF A new type of non-Ca2+-buffering Apo(a)-based fluorescent indicator for intraluminal Ca2+ in the endoplasmic reticulum.

J BIOL CHEM. 2006; 281(8): 5017-5025. [OPEN ACCESS] PubMed FullText FullText_MUG

** Schmidt, R; Schmidt, H; Pichler, M; Enzinger, C; Petrovic, K; Niederkorn, K; Horner, S; Ropele, S; Watzinger, N; Schumacher, M; Berghold, A; Kostner, GM; Fazekas, F C-reactive protein, carotid atherosclerosis, and cerebral small-vessel disease: results of the Austrian Stroke Prevention Study.

Stroke. 2006; 37(12):2910-2916 [OPEN ACCESS] PubMed FullText FullText_MUG Google Scholar

2005-Full papers/articles (Journal)

** Kipmen-Korgun, D; Osibow, K; Zoratti, C; Schraml, E; Greilberger, J; Kostner, GM; Jürgens, G; Graier, WF T-cadherin mediates low-density lipoprotein-initiated cell proliferation via the Ca(2+)-tyrosine kinase-Erk1/2 pathway.

J Cardiovasc Pharmacol. 2005; 45(5):418-430 PubMed FullText Google Scholar

** Kratky, D; Zimmermann, R; Wagner, EM; Strauss, JG; Jin, W; Kostner, GM; Haemmerle, G; Rader, DJ; Zechner, R Endothelial lipase provides an alternative pathway for FFA uptake in lipoprotein lipase-deficient mouse adipose tissue.

J Clin Invest. 2005; 115(1):161-167 [OPEN ACCESS] PubMed PUBMED Central FullText FullText_MUG Google Scholar

Reviews

** Kostner, KM; Kostner, GM Therapy of hyper-Lp(a).

Handb Exp Pharmacol. 2005; 8(170): 519-536. PubMed

 

Academic positions:


Emeritus Professor of Molecular Biology and Biochemistry, Medical University of Graz, Austria.

 

Research interests:


Lipid and lipoprotein metabolism; hemostasis; expression of genes involved in atherogenesis;atherogenesis; drug treatment of lipid disorders; genetics of lipid disorders.

 

Any other information:


Despite I retired as chairman of the Institute of Molecular Biology and Biochemistry in 2009, I am still very much involved in the research going one at our university.

 

What I think of the idea behind WebmedCentral:


Basically it looks quite promising. An important issue will be to clearly encompass it from other webb portals such as "Health Orbit" "DocCheck" and those of scientific societies.

 

Home Page:


http://www.medunigraz.at/mbbc/cms.php?pageName=GMK