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Dr. Ranjith Kumavath

Post-doc fellow
Central University of Kerala
Kerala
 

Brief Biography:


Education:
2003-2009: Ph.D. (Life-Sci…Microbial Biochemistry), University of Hyderabad, India.
2001-2003: M.Sc. (Bio-Chemistry), Sri Venkateswara University, Tirupati, India.
1996-2000: B.Sc. Sri Krishnadevaraya University.
1994-1996: Bi.P.C. Board of Intermediate Edu.
1994: SSC. Board of Secondary Edu.

 

Academic positions:


Post-Doctoral Researcher at School of Biomedical  Sciences, Mercer University, Savannah, GA, USA

 

Research interests:


1. Molecular biology: DNA, RNA, Plasmid isolation, Western blotting analysis, Primer designing, Site-Directed Mutagenesis, PCR, Gene cloning, and Recombinant Proteins Expression and Purification.
2. Protein Expression, Purification and Characterization: UV-vis spectroscopy, Native gels, SDS-PAGE, 2D-Electrophresis, Gel filtration, Affinity, Ion-exchange chromatography, FPLC, Protein digestion, and MALDI-TOF analysis.
3. Metabolites Purification and Structural elucidation: TLC, HPLC, LC-MS, IR, & NMR Spectroscopy.
4. Cell cultures

 

Any other information:


Awards and Professional affiliations:
1. Awarded Junior Research Fellowship (JRF & SRF), by University grants commission (UGC-RNF), Govt. of India (2003-2007).
2. Awarded UGC-Dr.D.S.Kothari Post-Doctoral Fellow, by University Grant Commission (UGC), New Delhi, India (August, 2008).
3. Post-Doctoral Research Fellow (PDF), in School of Biological Sciences, NanYang Technological University, 60-Nanyan Drives, Singapore. (March 2009).
4. Bio-Asia 2008 Innovation for young scientist award, presented paper (Feb, 2008).
5. Dr.K.V.Rao Memorial young scientist award-2008 nominated for paper presented.
6. Member Life time- Indian Association of medical microbiology
Publications: (published in reputed international journals:
1. Li Yan 1, Ranjith N.Kumavath1, Leo Wong E 1, Shubadra P1 Konstantin Pervushin 1*.NMR Structural determination of QFM-F mutation of N-domain of Human eukaryotic release factor (eRF1) and its recognition and mechanism of stop-codon UGA. Biochemistry (2011) MS- to be communicated. [Impact Factor. 3.226]
2. Ranjith N.Kumavath, Sasikala, Ch. and Ramana, Ch.V. Tryptophan ammonia lyase an enzyme catalyzes the formation of indole 3-acrylic acid from L-tryptophan isolated from Rubrivivax benzoatilyticus JA2. Journal of Bacteriology (2010) (MS-submitted) [Impact Factor. 3.94]
3. Ranjith N.Kumavath, Sasikala, Ch. and Ramana, Ch.V. Rubrivivaxin, a New Cytotoxic and Cyclooxygenase-I Inhibitory Metabolite from Rubrivivax benzoatilyticus JA2. World Journal of Microbiology and Biotechnology 27: 11-16(2011) [Impact Factor. 0.94]
4. Ranjith N.Kumavath, Sasikala, Ch. and Ramana, Ch.V. L-tryptophan catabolism by Rubrivivax benzoatilyticus JA2 occurs through indole 3-pyruvic acid pathway. Biodegradation. 21(5):825-32 (2010) [Impact Factor. 2.415]
5. Ranjith N.Kumavath, Sasikala, Ch. and Ramana, Ch.V. Production of Phenols and Alkyl Gallate-esters by Rhodobacter sphaeroides OU5. Curr. Microbiol.60 (2): 107-111 (2010). [Impact Factor. 1.33]  
6. N.K Ranjith, Ramana Ch.V and Sasikala Ch. Purification and characterization of 3, 4-dihydroxyphenylalanine oxidative deaminase from Rhodobacter sphaeroides OU5. Can J Microbiol. 54(10): 829-34 (2008) [Impact Factor. 1.262].
7. N.Kumavath Ranjith, Sasikala Ch and Ramana Ch.V. Rhodethrin: Novel indole terpenoid ether produced by Rhodobacter sphaeroides has Cytotoxic and Phytohormonal activities. Biotechnol. Lett.29 (9): 1399-402. (2007) [Impact Factor. 1.636].
8. N.K Ranjith, Sasikala Ch and Ramana Ch.V. Catabolism of L-phenylalanine and L-tyrosine by Rhodobacter sphaeroides OU5 occurs through 3, 4-dihydroxyphenylalanine. Res. Microbiol. 158(6): 506-11 (2007) [Impact Factor. 2.715].
9. Shanker, V, Rayabandla, S.M, Ranjith Nayak Kumavath, Chintalapati S and Chintalapati R. Light-dependent transformation of aniline to indole esters by the purple bacterium Rhodobacter sphaeroides OU5. Curr Microbiol. 52(6): 413-7 (2006) [Impact Factor. 1.33]
Reviewer:
1. Natural Product Research (Taylor & Francis).
2. Journal of Microbiology and antimicrobials.
3. Current Microbiology (Springer’s).
4. Analytical Biochemistry (Elsevier).
5. African journal of Biochemistry

 

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