Images in Clinical Medicine

By Dr. Abderrahman Elmazghi , Dr. Issam Lalya , Dr. Hanane Elkacemi , Prof. Tayeb Kebdani , Prof. Khalid Hassouni , Prof. Noureddine Benjaafar
Corresponding Author Dr. Issam Lalya
National Institute of Oncology , Rabat , - Morocco
Submitting Author Dr. Issam Lalya
Other Authors Dr. Abderrahman Elmazghi
Department of Radiotherapy, Teaching Hospital , Fes, - Morocco

Dr. Hanane Elkacemi
National Institute of Oncology , Rabat , - Morocco

Prof. Tayeb Kebdani
National Institute of Oncology , Rabat, - Morocco

Prof. Khalid Hassouni
Department of Radiotherapy, Teaching Hospital , Fes, - Morocco

Prof. Noureddine Benjaafar
National Institute of Oncology , Rabat, - Morocco


Dermatomyositis, Paraneoplastic Syndrome, Lung Cancer

Elmazghi A, Lalya I, Elkacemi H, Kebdani T, Hassouni K, Benjaafar N. Dermatomyositis Revealing Lung Cancer. WebmedCentral ONCOLOGY 2011;2(5):WMC001911
doi: 10.9754/journal.wmc.2011.001911
Submitted on: 02 May 2011 06:56:37 PM GMT
Published on: 03 May 2011 08:02:51 PM GMT


51 year-old-man, without history of disease, who had smoked 40-pack years, presented ten months before his admission, with an erythematous and scaly eruption over the extensor surfaces of the metacarpophalangeal joints and digits, knees were also affected ( illustration 1). The diagnosis of dermatomyositis was established after pathologic examination of muscular biopsy. Chest X-rays showed a left apical opacity. Chest and abdominal CT showed an apical lung tumor and right adrenal lesion suggestive of metastasis ( Illustration 2). CT-guided biopsy of the lung lesion revealed a squamous cell carcinoma. A systemic treatment was initiated, unfortunately the patient died following a septic shock, which occurred after 2 courses of chemotherapy. Dermatomyositis may be associated with malignancies type lymphoma or melanoma in 15% of adults over 40 years, however, the association with solid tumors is rare (1-2). The histology is variable: adenocarcinoma, squamous cell carcinoma, small cell carcinoma and others (2). Cancer treatment usually leads to a regression of symptoms of dermatomyotisis but the reappearance of clinical symptoms should call for a recurrence or distant metastasis (1)


1. Irwin M, Braverman MD. Skin manifestations of internal malignancy. Clinics in Geriatric Medicine2002; 18(1), 1-19  2. Yang Y, Fujita J, Tokuda M, Bandoh S, Ishida T. Lung cancer associated with several connective tissue diseases: with a review of literature. Rheumatol Int 2001;21(3):106 -11

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3 reviews posted so far

Interesting case
Posted by Dr. Youssef Bensouda on 18 May 2011 12:53:22 PM GMT

Posted by Prof. Esther Una Cidon on 04 May 2011 12:23:54 PM GMT

Dermatomyositis revealing lung cancer
Posted by Dr. Narendra Hulikal on 04 May 2011 03:56:40 AM GMT

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