Research articles
 

By Prof. Jordan Pop-Jordanov , Prof. Nada Pop-Jordanova
Corresponding Author Prof. Nada Pop-Jordanova
Pediatric Clinic, Faculty of Medicine, University of Skopje, Vodnjanska 17 - Republic of Macedonia 1000 Skopje
Submitting Author Prof. Jordan Pop-Jordanov
Other Authors Prof. Jordan Pop-Jordanov
Research Center for Energy, Informatic and Materials of the Macedonian Academy of Sciences and Arts, Krste Misirkov 2 - Republic of Macedonia 1000 Skopje

BRAIN

EEG, mental activity, arousal, brain rate, ELF, mobile phones

Pop-Jordanov J, Pop-Jordanova N. Mobile Phones, E E G And Mental Activity. WebmedCentral BRAIN 2010;1(12):WMC001370
doi: 10.9754/journal.wmc.2010.001370
No
Submitted on: 27 Dec 2010 10:41:48 AM GMT
Published on: 28 Dec 2010 12:52:33 PM GMT

Abstract


Background: The published results about possible mental effects of mobile phone exposure are still inconsistent and inconclusive.

Methods: The sigmoid arousal-frequency correlation combined with the brain rate concept is used to characterize the effects of mobile phones on mental states.

Results: Pronounced asymmetries and individualities in brain rate values, characterizing EEG spectral shifts towards overarousal or underarousal, have been obtained.

Conclusion: The mental consequences of mobile phone use could be, in principle, detrimental or beneficial, depending on the individual initial EEG spectra and the different exposure frequencies from mobile phone technologies. Thereby, brain rate can serve as a useful preliminary indicator.

Introduction


Worldwide concern about possible mental effects of mobile phone (MP) exposure lasts for more than two decades [1-2]. However, the published results are still inconsistent and inconclusive [3-5]. So, in two recent documents from competent organizations (World Health Organization - WHO and International Commission on Non-Ionizing Radiation Protection - ICNIRP) it is stated, respectively: “To date, results of epidemiological studies provide no consistent evidence of a causal relationship between radiofrequency exposure and any adverse health effect. Yet, these studies have too many limitations to completely rule out an association”[4]; and: ”The evidence for neurobehavioral effects on brain electrical activity, cognition, sleep and mood in volunteers exposed to low frequency electric and magnetic fields is much less clear”[5].

 The aim of this article is to present a possible explanation for the ambiguous and inconsistent evidence about MP effects on mental activity. In addition, the applicability of brain rate concept [6] for indicating MP influences is considered.

Empirical evidence


Starting key question is: which EEG frequencies are relevant for mental activity? The well established empirical results show that these are frequencies in the extremely low (ELF) range of bellow one hundred Hz. Moreover, it appeared that the states of arousal are somehow proportional to the EEG activity represented by different frequency bands: from delta (0.5-4 Hz) till gamma (30-50 Hz). Thereby, the empirical data have shown that the delta band corresponds to deep sleep stages 3-4, theta to drowsiness and sleep stages 1-2, alpha to relaxed state, while SMR, beta and gamma to alert state, anxiety and peak performance, respectively [7, 8].

Simultaneously, ELF frequencies of the same range are also emitted by MPs of different technologies (Illustration1). Consequently, an influence of MP on EEG and mental activity is quite feasible and could be diverse [9, 10]. Actually, a number of studies on animals (Illustration2) and humans (Illustration3) has confirmed this kind of MP effects.

Modeling


Analysing the empirical input-output activation, arousal can be represented as a sigmoid function [11]. An analytical expression of the same sigmoid dependence has been derived by a quantum theoretical approach, based on the transition probabilities from the interaction of brain electric field with neuronal dipoles [12]. Combining these theoretical results with the mentioned empirical data, a summarized arousal-frequency correlation can be represented (Illustration4) [13].

However, the actual electric field in the brain (both endogenous and externally modulated) is not monochromatic, but spectral, characterized by a time-changing frequency distribution. Consequently, a spectrum weighted frequency (brain rate) parameter was introduced [6], as a useful general indicator of mental state (in parallel with temperature, blood pressure or hearth rate, indicating different bodily states) [Illustration5].

Results


The brain rate values for different mental states (sleep stages and some mental disorders), showing underarousal or overarousal, are displayed in Illustration6.

 The distribution of mean brain rate values (for 40 healthy adults), indicating the changes in different cortical regions (Frontal/Back, Left/Right and midline) are shown in Illustration7.

 Summarizing the published results, illustrations 8-10 show pronounced asymmetries and individualities of MP exposure effects on human EEG, which lead to corresponding variations of brain rate as indicator of mental activity.

Conclusions


The inconsistent and inconclusive evidence about MP mental effects could be due to subtle interplay of spectral individualities and radiation specifics, representing neurophysical substrate of mental processes. Having in mind pronounced individual differences concerning EMF effects, it is suggested to refine accordingly the sampling procedure, differentiating specific subgroups for studying.

 Actually, the mental consequences of MP could be detrimental or beneficial, depending on the individual initial EEG spectra and the different exposure frequencies from MP technologies. Moreover, MP use can be considered as a sort of brain gymnastics or neurofeedback training (but still random and not “knowledge based”).

 Thereby, EEG spectrum weighted frequency (brain rate), characterizing the level of mental arousal, can serve as a useful preliminary indicator of possible MP influences, and a training parameter.

Acknowledgement


The study was partly supported by EU/ESF COST Action BM0704: Emerging EMF Technologies and Health Risk Management.

Authors contributions


JPJ contributed to neurophysical modeling.
NPJ contributed to neuromedical studies.
Both authors participated in the design and approved the final manuscript.

References


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Reviews
4 reviews posted so far

The authors are thankful for your review and comments. In the revised manuscript , published on 30 January 2011, (1) the sections of results and discussion are expanded and (2) the information from il... View more
Responded by Prof. Jordan Pop-Jordanov on 31 Jan 2011 10:56:19 AM GMT

Mobile Phones, E E G And Mental Activity
Posted by Prof. Giedrius Varoneckas on 04 Jan 2011 09:16:28 AM GMT

The authors are thankful for your valuable comments and suggestions. In the revised manuscript, published on 30 January 2011, all of them are taken into account, namely: (1) the sections of results an... View more
Responded by Prof. Jordan Pop-Jordanov on 31 Jan 2011 10:56:52 AM GMT

The authors are grateful for your valuable review and comments. Concerning the tables and illustrations, in the revised paper, published on 30 January 2011, their quality is improved and the number i... View more
Responded by Prof. Jordan Pop-Jordanov on 31 Jan 2011 10:59:22 AM GMT

Mobile Phones and Brain
Posted by Prof. Nataliya A Babenko on 29 Dec 2010 03:13:00 PM GMT

The authors are thankful for your valuable comments and suggestions. In the revised paper, published on 30 January 2011, more attention is paid to the discussion, the quality of illustrations is impro... View more
Responded by Prof. Jordan Pop-Jordanov on 31 Jan 2011 11:00:07 AM GMT

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