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Aggressive Nasal Extranodal Nk/t Cell Lymphoma: Case Report
By Dr. Laurindo M Sassi , Dr. Juliana L Schussel , Dr. Roberta T Stramandinoli , Dr. Fernando L Zanferrari , Dr. Nils G Skare , Dr. Sergio Ioshii
Submited on: 26 Feb 2011 04:11:16 PM GMT
Published on: 27 Feb 2011 06:50:02 PM GMT
 
Reveiw on NK/T cell lymphoma
Posted by Dr. Abu Dzarr on 14 Apr 2011 03:48:52 PM GMT

1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? No
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    This is a good write up. 

     

    I am just curious to know, which chemo regime was used.  Most of us in Oriental Asia will take note of the positive outcome from Hong Kong and Korea studies using aspariginase containing SMILE protocol. 


    I postulate this patient has stage II disease but I think the author should state this in the report.  What kind of response did the patient achieve post therapy, PR or CR.  NK/T cell lymphoma are FDG-avid (Wu et al, 2011) and post therapy staging may be useful to determine tumor response.


    Considering that the time between relapse and death was 5 months, did the patient receive any second line therapy.  Some naration of event during this stage may be forthcoming.

    References:
    WU, H. B., WANG, Q. S., WANG, M. F., LI, H. S., ZHOU, W. L., YE, X. H. & WANG, Q. Y.(2011). Utility of 18F-FDG PET/CT for staging NK/T-cell lymphomas. Nucl Med Commun, 31, 195-200.

  • Competing interests:
    None
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    Yes
  • References:
    ZAIDAH, A. W., ROSHAN, T. M., SUHAIR, A., R, H., RAPIAAH, M. & DZARR, A. A. (2006). Natural Killer (nk)-large Granular Lymphocyte Leukaemia: A Case Report. Haema, 9(2) 290-292
  • Experience and credentials in the specific area of science:

    Hematooncologist

  • How to cite:  Dzarr A .Reveiw on NK/T cell lymphoma[Review of the article 'Aggressive Nasal Extranodal Nk/t Cell Lymphoma: Case Report ' by Ioshii S].WebmedCentral 2011;2(4):WMCRW00677
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Aggressive Nasal Extranodal Nk/t Cell Lymphoma: Case Report
Posted by Dr. Paulo Henrique Braz-Silva on 13 Apr 2011 12:04:42 PM GMT

1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? No
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? No
9 Are the illustrations and tables necessary and acceptable? No
10 Are the references adequate and are they all necessary? No
11 Are the keywords and abstract or summary informative? No
  • Other Comments:

    Good writting and interesting case report of an uncommon lesion.

  • Competing interests:
    No
  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    Yes
  • References:
    1. Specific infiltration of langerin-positive dendritic cells in EBV-infected tonsil, Hodgkin lymphoma and nasopharyngeal carcinoma. Braz-Silva PH, Vitale S, Butori C, Guevara N, Santini J, Magalh?es M, Hofman P, Doglio A. Int J Cancer. 2011 May 1;128(10):2501-8. doi: 10.1002/ijc.25597. Epub 2010 Oct 8. 2.Usefulness of oral cytopathology in the diagnosis of infectious diseases. Braz-Silva PH, Magalh?es MH, Hofman V, Ortega KL, Ilie MI, Odin G, Vielh P, Hofman P. Cytopathology. 2010 Oct;21(5):285-99. Epub 2010 Jul 13. Review. 3.HIV-associated oral plasmablastic lymphoma and role of adherence to highly active antiretroviral therapy. Francischini E, Martins FM, Braz-Silva PH, Magalh?es MH, Ortega KL. Int J STD AIDS. 2010 Jan;21(1):68-70. Epub 2009 Nov 2. 4.Detection of the Epstein-Barr virus (EBV) by in situ hybridization as definitive diagnosis of hairy leukoplakia. Braz-Silva PH, de Rezende NP, Ortega KL, de Macedo Santos RT, de Magalh?es MH. Head Neck Pathol. 2008 Mar;2(1):19-24. Epub 2008 Feb 8. 5. Detection of Epstein-Barr virus (EBV) in the oral mucosa of renal transplant patients. Braz-Silva PH, Ortega KL, Rezende NP, Nunes FD, Magalh?es MH. Diagn Cytopathol. 2006 Jan;34(1):24-8.
  • Experience and credentials in the specific area of science:

    I'm an Oral Pathologist and my investigation area is neoplasia associated with herpesvirus, specially EBV.

  • How to cite:  Braz-Silva P .Aggressive Nasal Extranodal Nk/t Cell Lymphoma: Case Report[Review of the article 'Aggressive Nasal Extranodal Nk/t Cell Lymphoma: Case Report ' by Ioshii S].WebmedCentral 2011;2(4):WMCRW00669
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