Is the subject of the article within the scope of the subject category?
Yes
2
Are the interpretations / conclusions sound and justified by the data?
Yes
3
Is this a new and original contribution?
Yes
4
Does this paper exemplify an awareness of other research on the topic?
Yes
5
Are structure and length satisfactory?
Yes
6
Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience?
No
7
Can you suggest any reductions in the paper, or deletions of parts?
No
8
Is the quality of the diction satisfactory?
No
9
Are the illustrations and tables necessary and acceptable?
No
10
Are the references adequate and are they all necessary?
Yes
11
Are the keywords and abstract or summary informative?
Yes
Other Comments:
The topic of the manuscript is interesting. Salpingectomy during abdominal hysterectomy (without the removal of ovaries) has recently been a subject of debate. As the ovarian blood supply is dual (i.e. from the branches of the uterine artery and directly from the ovarian artery), preservation of the utero-ovarian branches with total salpingectomy might theoretically preserve the blood supply of the ovaries. However, all of the studies on this topic have not revealed positive results. Another potential advantage of complete fallopian tube removal during hysterectomy might be prophylaxis against subsequent tubal malignancies. Although primary tubal carcinomas are relatively rare, some recent evidence disputes that the initial site for the development of some of the so called epithelial ovarian carcinomas are in fact the tubal epithelium. If this is proven to be true, then total salpingectomy during hysterectomy can have additional benefits for the prevention of clinical ovarian cancers.
Thus, the present preliminary study throws a light on this debate, and concludes that complete excision of fallopian tubes during scheduled abdominal hysterectomies might preserve ovarian blood flow and function.
However, the following points need to be mentioned regarding the manuscript:
A statistical power analysis is missing. How did the authors exactly calculate the sample size? If there were no such calculations, what was the power of the study to detect differences (given the number of hysterectomies included)?
The presentation of change in parameters over time is confusing. For example, the sentence "Significant difference between both groups postoperatively" is not clear. For better demonstration, the mean values can be plotted onto three separate figures that include values obtained from both groups: 1) No. of antral follicles and mean ovarian volume. 2) FSH, LH, E2, and 3) RI and PI. Therefore, change over time and comparisons among groups can be followed more clearly.
Please do not use ampersand logogram in scientific texts.
The manuscript needs some language and style editing. The styles of references have spelling mistakes, as well.
Competing interests: None
Invited by the author to review this article? : Yes
Have you previously published on this or a similar topic?: Yes
References:
Sezik M, Ozkaya O, Demir F, Sezik HT, Kaya H. Total salpingectomy during abdominal hysterectomy: effects on ovarian reserve and ovarian stromal blood flow. J Obstet Gynaecol Res. 2007; 33(6): 863-9.
Experience and credentials in the specific area of science:
I published on a similar topic, as indicated below.
I am also an active researcher use of Doppler in clinical obstetrics and gynecology, and published several articles on that topic.
How to cite: Sezik M .Comment on the article by Nouh A et al[Review of the article 'Total Salpingectomy During Abdominal Hysterectomy Preserves Ovarian blood flow and Function ' by Seleim B].WebmedCentral 2011;2(3):WMCRW00589
The topic of the manuscript is interesting. Salpingectomy during abdominal hysterectomy (without the removal of ovaries) has recently been a subject of debate. As the ovarian blood supply is dual (i.e. from the branches of the uterine artery and directly from the ovarian artery), preservation of the utero-ovarian branches with total salpingectomy might theoretically preserve the blood supply of the ovaries. However, all of the studies on this topic have not revealed positive results. Another potential advantage of complete fallopian tube removal during hysterectomy might be prophylaxis against subsequent tubal malignancies. Although primary tubal carcinomas are relatively rare, some recent evidence disputes that the initial site for the development of some of the so called epithelial ovarian carcinomas are in fact the tubal epithelium. If this is proven to be true, then total salpingectomy during hysterectomy can have additional benefits for the prevention of clinical ovarian cancers.
Thus, the present preliminary study throws a light on this debate, and concludes that complete excision of fallopian tubes during scheduled abdominal hysterectomies might preserve ovarian blood flow and function.
However, the following points need to be mentioned regarding the manuscript:
None
Yes
Yes
Sezik M, Ozkaya O, Demir F, Sezik HT, Kaya H. Total salpingectomy during abdominal hysterectomy: effects on ovarian reserve and ovarian stromal blood flow. J Obstet Gynaecol Res. 2007; 33(6): 863-9.
I published on a similar topic, as indicated below.
I am also an active researcher use of Doppler in clinical obstetrics and gynecology, and published several articles on that topic.