Submited on: 23 Oct 2011 11:59:34 AM GMT
Published on: 23 Oct 2011 12:22:16 PM GMT
 
A clearly defined relationship between neurobiochemistry, neuroanatomy and sleep
Posted by Mr. Nick L'italien on 10 Nov 2016 08:05:45 PM GMT Reviewed by Interested Peers

  • What are the main claims of the paper and how important are they?

    A large interconnected netwrok involving neurotransmitters, hormones, genetics, and neuroanatomy play a role in the sleep-wake system and REM/non-REM transitions. Investigating this complicated system as a whole picture instead of individual parts is critical to further develop the cognitive neuroscience of sleep and its affects on daily life.


  • Are these claims novel? If not, please specify papers that weaken the claims to the originality of this one.

    No, but they are a review of the research within the past decade. 


  • Are the claims properly placed in the context of the previous literature?

    Yes 


  • Do the results support the claims? If not, what other evidence is required?

    The references support the claims, however, additional, up-to-date references should be added if they author were to revisit a review of this subject 


  • If a protocol is provided, for example for a randomized controlled trial, are there any important deviations from it? If so, have the authors explained adequately why the deviations occurred?

    NA 


  • Is the methodology valid? Does the paper offer enough details of its methodology that its experiments or its analyses could be reproduced?

    NA 


  • Would any other experiments or additional information improve the paper? How much better would the paper be if this extra work was done, and how difficult would such work be to do, or to provide?

    NA 


  • Is this paper outstanding in its discipline? (For example, would you like to see this work presented in a seminar at your hospital or university? Do you feel these results need to be incorporated in your next general lecture on the subject?) If yes, what makes it outstanding? If not, why not?

    Yes, the realm of cognitive neuroscience needs further discussion and inclusion to elucidate the most unknown topics, such as sleep. 


  • Other Comments:

    NA 

  • Competing interests:

  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    Background in Biochemistry and Psychology

  • How to cite:  L'italien N .A clearly defined relationship between neurobiochemistry, neuroanatomy and sleep[Review of the article 'Understanding the Interplay between Neurobiochemistry of Sleep-wake Systems and Cognition ' by Sadeghniaat K].WebmedCentral 2016;7(11):WMCRW003308
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    Authors focus on the neurochemistry of brain circuitries involved in sleep and wake systems plus the interrelation between sleep parameters and cognitive functions. The review was well written,  structured and illustrated. Future directions were poin out. Authors pay attention that data analyzed in the article were very important for fundamental research and for study of different pathological states, such as Parkinson’s, Alzheimer’s, Multiple Sclerosis, Schizophrenia, Depression, Anxiety and Post Traumatic Stress Disorders which have impaired sleep . These impairments are partly resulted from disrupted neurochemistry in the brain leading to an inefficient sleep and inappropriate vigilance with incompetent cognitive functions.

  • Competing interests:
    No
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    Yes
  • References:
    1. Bondarenko L.A., Babenko N.A. Effect of long-term around the clock illumination on rabbit serum phospholipids. Russian Journal of Physiology. 2006, 92(3):318-23. 2. Babenko N.A., Semenova Ya.A., Kharchenko V.S. Effects of fat-enriched diet on the content of sphingolipids in the brain and on cognitive functions in old rats. Neurophysiology, 2009, Vol. 41, ? 4, P. 258-263. 3. Babenko NA, Semenova YaA: Effects of long-term fish oil-enriched diet on the sphingolipid metabolism in brain of old rats. Experimental Gerontology, 2010, 45: 375-380. 4. Babenko N.A., Semenova Ya.A. Sphingolipid turnover in the hippocampus and cognitive dysfunction in alcoholized rats: correction with the help of alimentary n-3 fatty acids. Neurophysiology - 2010, Vol. 42, ? 3, P. 169-174. 5. Babenko N.A., Semenova Ya.A. Effects of exogenous phosphatidylserine on cognitive functions and phospholipid metabolism in the hippocampus of aged rats. Neuroscience and Behavioral Physiology. - 2011, Vol. 41, ? 1, P. 97-101.
  • Experience and credentials in the specific area of science:

    Neurobiochemistry: lipid turnover and hormones signal trusduction at different models of brain pathology

  • How to cite:  Babenko N A.The Interplay between Neurobiochemistry of Sleep-wake Systems and Cognition [Review of the article 'Understanding the Interplay between Neurobiochemistry of Sleep-wake Systems and Cognition ' by Sadeghniaat K].WebmedCentral 2016;2(10):WMCRW001042
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