Submited on: 08 Dec 2015 05:46:12 AM GMT
Published on: 10 Dec 2015 10:51:45 AM GMT

  • What are the main claims of the paper and how important are they?

    The locomotor characteristics of the Uner Tan Syndrome Cases cheracterize uniquely neurological disorder. Uner Tan Syndrome Cases can be regarded as the unpredictable outcome of an adaptive self-organizing process within a genetically disordered brain. The results are interpreted in line with locomotor reverse evolution, although the primates constitute a distinct group because their upper limbs are specialized for skilled hand movements with specific supraspinal motor control.

  • Are these claims novel? If not, please specify papers that weaken the claims to the originality of this one.


    Healthy individuals could not mimic the quadrupedal locomotion of Uner Tan Syndrome cases, indicating that quadrupedal locomotion in healthy human individuals is not similar to the Uner Tan Syndrome cases: the UTS quadrupedal style is unique in this context.

    A phenotypic re-emergence of quadrupedal locomotion would be enough to show the reverse locomotor evolution by definition, without considering its details.

  • Are the claims properly placed in the context of the previous literature?


  • Do the results support the claims? If not, what other evidence is required?


  • If a protocol is provided, for example for a randomized controlled trial, are there any important deviations from it? If so, have the authors explained adequately why the deviations occurred?

    Yes, the authors explained adequately  the results and deviations.

  • Is the methodology valid? Does the paper offer enough details of its methodology that its experiments or its analyses could be reproduced?

    The qualitative new analysis of the locomotor characteristics in the UTS cases demonstrated this syndrome may constitute a unique group uniquely neurological disorder.

  • Would any other experiments or additional information improve the paper? How much better would the paper be if this extra work was done, and how difficult would such work be to do, or to provide?


  • Is this paper outstanding in its discipline? (For example, would you like to see this work presented in a seminar at your hospital or university? Do you feel these results need to be incorporated in your next general lecture on the subject?) If yes, what makes it outstanding? If not, why not?


  • Other Comments:

    The results were interpreted in line with locomotor reverse evolution and Darwinian medicine. It should, however, be noted that no one is certain who our real ancestors were, which makes it impossible to be conclusive in this context. On the other hand, the scientific literature showed that evolution in reverse is an experimentally proven fact.

  • Competing interests:
  • Invited by the author to review this article? :
  • Have you previously published on this or a similar topic?:
  • References:


  • Experience and credentials in the specific area of science:

    Experience in Neuroscience.

  • How to cite:  Dushanova J .The locomotor characteristics of the Uner Tan Syndrome Cases cheracterize uniquely neurological disorder.[Review of the article 'Quadrupedal Locomotor Characteristics of Uner Tan Syndrome Cases, Healthy Humans, and Nonhuman Primates in Evolutionary Perspectives ' by Tan U].WebmedCentral 2015;6(12):WMCRW003264
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