WebmedCentral.com :: Article Review View

Submited on: 05 Nov 2010 11:14:23 AM GMT

Published on: 06 Nov 2010 10:25:09 AM GMT

Posted by Dr. Amin Malik Shah Abdul Majid on 11 Dec 2010 08:55:53 AM GMT

1	Is the subject of the article within the scope of the subject category?	Yes
2	Are the interpretations / conclusions sound and justified by the data?	Yes
3	Is this a new and original contribution?	Yes
4	Does this paper exemplify an awareness of other research on the topic?	Yes
5	Are structure and length satisfactory?	Yes
6	Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience?	Yes
7	Can you suggest any reductions in the paper, or deletions of parts?	No
8	Is the quality of the diction satisfactory?	Yes
9	Are the illustrations and tables necessary and acceptable?	Yes
10	Are the references adequate and are they all necessary?	Yes
11	Are the keywords and abstract or summary informative?	Yes

Other Comments:
The article is well written and the work carried out provides a clear evidance of the level of pro-apoptosis activity of C18 and C12 ceramide and brain derived non-hydroxy fatty acid ceramide. The work would have been more robust if DNA fragmentation and also cell morphological evidence of apoptosis was included.
Competing interests:
none
Invited by the author to review this article? :
No
Have you previously published on this or a similar topic?:
No
References:
None
Experience and credentials in the specific area of science:

Cancer pharmacology
How to cite: Abdul Majid A .Natural C18:0-ceramide Induces Cellular Sphingolipid Accumulation And Apoptosis [Review of the article 'Natural C18:0-ceramide Induces Cellular Sphingolipid Accumulation And Apoptosis ' by Geilen C].WebmedCentral 2010;1(12):WMCRW00225

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