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, Dr. Nithya Swaminathan

, Dr. Leslie E Lewis

Submited on: 29 Dec 2011 11:51:20 AM GMT

Published on: 30 Dec 2011 04:25:42 PM GMT

A possible role of antenatal vitamin K administration in preventing epiphyseal stippling in fetal hyadantoin syndrome

Posted by Anonymous Reviewer on 08 Sep 2012 02:27:34 PM GMT

What are the main claims of the paper and how important are they?
The role of antenatal administration of vitamin K in preventing epiphyseal stippling in fetal hydantoin syndrome. The mothers who are on phenytoin during antenatal period should be given vitamin K in preventing bone resorption in fetus.
Are these claims novel? If not, please specify papers that weaken the claims to the originality of this one.
Yes
Are the claims properly placed in the context of the previous literature?

Yes
Do the results support the claims? If not, what other evidence is required?

Yes
If a protocol is provided, for example for a randomized controlled trial, are there any important deviations from it? If so, have the authors explained adequately why the deviations occurred?

Yes
Is the methodology valid? Does the paper offer enough details of its methodology that its experiments or its analyses could be reproduced?

Yes
Would any other experiments or additional information improve the paper? How much better would the paper be if this extra work was done, and how difficult would such work be to do, or to provide?

The author should have provided the picture of the baby to authenticate the article. The dose of vitamin K should have been provided and till how long to provide and when to start.
Is this paper outstanding in its discipline? (For example, would you like to see this work presented in a seminar at your hospital or university? Do you feel these results need to be incorporated in your next general lecture on the subject?) If yes, what makes it outstanding? If not, why not?
Yes
Other Comments:
I must compliment the author for excellent article written. However, the author should have provided the picture of the baby to authenticate the article. The dose of vitamin K should have been provided and till how long to provide and when to start.
Competing interests:
No
Invited by the author to review this article? :
No
Have you previously published on this or a similar topic?:
No
References:
None
Experience and credentials in the specific area of science:

Been working in one of the busy neonatal care unit.
How to cite: Anonymous.A possible role of antenatal vitamin K administration in preventing epiphyseal stippling in fetal hyadantoin syndrome[Review of the article 'A Possibile role of Antenatal Vitamin K Administration in Preventing Epiphyseal Stippling in Fetal Hydantoin Syndrome ' by Lewis L].WebmedCentral 2012;3(9):WMCRW002227

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