WebmedCentral Editor

Dr. Ashok Singh

Research Associate
Department of Human Oncology; Wisconsin Institute for Medical Research

Brief Biography:

The keratinocyte stem cells (KSCs) have an important role in maintaining normal structure and function of the epidermis and the hair follicles of skin. These keratinocyte stem cells are thought to be important key players in various skin diseases including skin cancers. Presently, I am working in the field of hair follicle stem cells and their connection with Squamous cell carcinoma via various cytokines.

Hormel Post-Doctoral Fellow (15 April 2009 – 28 Dec 2011) Hormel Institute, University of Minnesota, Austin MN, USA

Post-Doctoral Fellow (28 April 2008 – 13 April 2009) Mayo Clinic, Scottsdale, AZ, USA

Junior Research Fellow & Senior Research Fellow -CSIR (2003-2005 & 2005-2007) Central Drug Research Institute, Lucknow, India.

PhD: Jawaharlal Nehru University, New Delhi (India)

M.Sc. (Zoology, 1999-2001): University of Allahabad, Allahabad. Uttar Pradesh. India

B.Sc. (Zoology, Botany, Chemistry, 1995-1998): Birla Constitute College, HNBGU, Garhwal University, Srinagar Garhwal. Uttarakhand. India

Academic positions:

Academic progression:

1. January 2012–till now: Research Associate; Department of Human Oncology, University of Wisconsin, Madison, Wisconsin, USA 2. 15 April 2009–28 Dec 2011: Hormel Post-Doctoral Fellow; Hormel Institute, University of Minnesota, Austin MN, USA 3. 28 April 2008–13 April 2009: Post-Doctoral Fellow; Mayo Clinic, Scottsdale, AZ, USA 4. 2005-2007: Senior Research Fellow-CSIR; Central Drug Research Institute, Lucknow, India. 5. 2003-2005: Junior Research Fellow-CSIR; Central Drug Research Institute, Lucknow, India.

Honors/awards

1. National eligibility test for Junior Research Fellowship (NET-JRF, meritorious fellowship) and lectureship by Council of Scientific and Industrial Research (CSIR), Govt. of India, CSIR-UGC (NET) June 2002. Web link: http://en.wikibooks.org/wiki/Chemical_Sciences:_A_Manual_for_CSIR-UGC_National_Eligibility_Test_for_Lectureship_and_JRF/About_NET_Examination 2. National eligibility test for Junior Research Fellowship (NET-JRF, meritorious fellowship) and lectureship by Council of Scientific and Industrial Research (CSIR), Govt. of India, CSIR-UGC (NET) December 2002. 3. State level eligibility test for lectureship (SLET), Rajasthan Public Service Commission, Ajmer, Rajasthan, Govt. of India. Accredited by the University Grants Commission (UGC); New Delhi, 2001. Web link: http://universaled.net/SLET-Exam-in-Rajasthan.php

Research interests:

Human Oncology, Skin biology

Any other information:

Publications

1. Singh, A., Singh, A., Sand, J.M., Heninger, E., Hafeez, B.B., and Verma, A. K. Protein Kinase C?, which is linked to ultraviolet radiation-induced development of squamous cell carcinomas, stimulates rapid turnover of adult hair follicle stem cells. Journal of Skin Cancer. Vol 2013, Article ID 452425, 13 pages. [Google Citations= ] 2. Singh, A., (2013). What is the gene definition now and what is next. Chronicles of Young Scientist. Vol 4, Issue 1, 74. 3. Singh, A., Mitra, A.K., Mishra, P., Paul, A.K., Sharma, S., and Rath, S. K. (2013). Screening of PEO1 and mitochondrial genes in sporadic cases of ophthalmoplegia. Chronicles of Young Scientist. Vol 4, Issue 1, 40-45. 4. Goswami R, Singh A, Gupta N; Indian Genome Variation Consortium, Rani R. Presence of strong association of the major histocompatibility complex (MHC) class I allele HLA-A*26:01 with idiopathic hypoparathyroidism. J Clin Endocrinol Metab. 2012 Sep;97(9):E1820-4. doi: 10.1210/jc.2012-1328. Epub 2012 Jun 20. (Author as a collaborator). [Google Citations= 1] 5. Singh, A., Mitra, A.K., Indian Genome Variation Consortium, and Rath, S. K. (2012). Analysis of single-nucleotide polymorphisms of PEO1 gene in 55 ethnic groups of India. Chronicles of Young Scientist. Vol 3, Issue 4, 304-309. 6. Singh, A., Park, H., Kangsamaksin, T., Singh, A., Readio, N., and. Morris, RJ. (2012). Keratinocyte Stem Cells and the Targets for Nonmelanoma Skin Cancer. Photochemistry and Photobiology. Vol 88, 1099-1110. [Google Citations= 2] 7. Singh, A., Morris RJ. (2012). Innate immunity and the regulation and mobilization of Keratinocyte stem cells: are the old players playing a new game? Journal of Experimental Dermatology. Vol 21, 660–664. [Google Citations= 1] 8. Singh, A., Morris RJ. (2010). The Ying and Yang of bone morphogenetic proteins in Cancer. Cytokines and Growth Factor Reviews. Vol 21 (4), 299-313. [Google Citations= 29] 9. Aggarwal S, Negi S, Jha P, Singh PK, Stobdan T, Pasha MA, Ghosh S, Agrawal A; Indian Genome Variation Consortium, Prasher B, Mukerji M; The Indian Genome Variation Consortium is composed of the following additional members:. Collaborators (151) Brahmachari SK, Majumder PP, Mukerji M, Habib S, Dash D, Ray K, Bahl S, Singh L, Sharma A, Roychoudhury S, Chandak GR, Thangaraj K, Parmar D, Sengupta S, Bharadwaj D, Rath SK, Singh J, Jha GN, Virdi K, Rao VR, Sinha S, Singh A, et al. (2010). The full list of authors participating in the Indian Genome Variation Consortium can be found at http://igvbrowser.igib.res.in/gbrowse/igvc.html. EGLN1 involvement in high-altitude adaptation revealed through genetic analysis of extreme constitution types defined in Ayurveda. Proceedings of National Academy of Sciences U S A. 2010 Nov 2; 107(44):18961-18966. (Author as a collaborator). [Google Citations= 37] 10. Indian Genome Variation Consortium. (2008). Genetic landscape of people of India: a canvas for disease gene exploration. Journal of Genetics, Vol-87, 3-20. [Google Citations= 136] 11. Mitra, A.K., Singh, N., Singh, A., Garg, V.K., Agarwal, A., Sharma, M., Chaturvedi, R., and Rath, S.K. (2008): Association of polymorphisms in Base Excision Repair genes with the risk of Breast Cancer: a case-control study in North Indian women. Oncology Research. Vol-17 (3): 127-135. [Google Citations= 15] 12. Singh, A., Chandra, S., Gupta, S.K., Chauhan, L.K.S., and Rath, S.K. (2007): Mutagenicity of leachates from Industrial Solid Wastes using Salmonella Reverse Mutation Assay. Ecotoxicology and Environmental safety. Vol-66 (2): 210-216. [Google Citations= 8] 13. The Indian Genome Variation database Consortium (2005): The Indian Genome Variation database (IGVdb): An overview, Human Genetics.Vol-118: 1-11. [Google Citations= 44] 14. Singh, A., Mitra, A.K., Sharma, R.K. and Rath, S. K. (2004): Pharmacogenomics-A new approach to Drug Development, Drugs and Pharmaceuticals Current R & D Highlights. Vol-27 (3): 8-17.

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Home Page:

http://www.humonc.wisc.edu/index.php/Ashok_Singh