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Dr. Weili Cai

Postdoc Fellow
National Institute of Health
9000 Rockville Pike Bldg18T Rm. 101
 

Brief Biography:


• 2001 B.S. Biology, Beijing Forestry University, Beijing, China
• 2004 M.S. Cell Biology, Beijing Normal University, Beijing,China
• 2011 PhD Molecular Cellular and Developmental Biology, Iowa State University, Ames, IA, USA • 2012-Present Postdoc Fellow Eunice Kennedy Shriver National Institute of Child Health and Human Development National Institutes of Health, MD, USA

 

Academic positions:


Postdoc Fellow

 

Research interests:


Nuclear Organization, Chromosome Organization, Oogenesis, Mitosis regulation, Membrane trafficking

 

Any other information:


Publications

Journal Papers

1. Li Y*, Cai W*, Wang C, Yao C, Bao X, Deng H, Girton J, Johansen J and Johansen KM.Domain Requirements of the JIL-1 Tandem Kinase for Histone H3S10 Phosphorylation and Chromatin Remodeling in Vivo. J Biol Chem. 2013 May 30. [* These authors have equal contribution]
2. Wang C, Yao C, Li Y, Cai W, Bao X, Girton J, Johansen J and Johansen KM. Evidence against a Role for the JIL-1 Kinase in H3S28 Phosphorylation and 14-3-3 Recruitment to Active Genes in Drosophila. PLoS One. 2013 Apr 30;8(4)
3. Wang C, Cai W, Li Y, Girton J, Johansen J, Johansen KM. H3S10 phosphorylation by the JIL-1 kinase regulates H3K9 dimethylation and gene expression at the white locus in Drosophila. Fly (Austin). 2012 Apr 1;6(2).
4. Yao C, Ding Y, Cai W, Wang C, Girton J, Johansen KM, Johansen J. The chromodomain-containing NH(2)-terminus of Chromator interacts with histone H1 and is required for correct targeting to chromatin. Chromosoma. 2012 Apr; 121(2):209-20.
5. Wang C, Cai W, Deng H, Bao X, Girton J, Johansen J and Johansen KM. The Epigenetic H3S10ph Marker is Required for Counteracting Heterochromatic Spreading and Gene Silencing in Drosophila. Journal of Cell Science. 2011 Dec 15;124(Pt 24):4309-17.
6. Deng H, Cai W, Wang C, Lerach S, Delattre M, Girton J, Johansen J, Johansen KM. JIL-1 AND SU(VAR)3-7 Interact Genetically and Counteract Each Other's Effect on Position Effect Variegation in Drosophila. Genetics. 2010 Aug;185(4):1183-927.
7. Boeke J, Regnard C, Cai W, Johansen J, Johansen KM, Becker PB, Imhof A. Phosphorylation of SU(VAR)3-9 by the chromosomal kinase JIL-1. PLoS One. 2010 Apr 6;5(4):e10042
8. Cai W, Jin Y, Girton J, Johansen J, Johansen KM. Preparation of Drosophila polytene chromosome squashes for antibody labeling. J Vis Exp. 2010 Feb 9;(36). pii: 1748. doi: 10.3791/1748.
9. Qi H, Yao C, Cai W, Girton J, Johansen KM, Johansen J.Asator, a tau-tubulin kinase homolog in Drosophila localizes to the mitotic spindle. Dev Dyn. 2009 Dec;238(12):3248-56.
10. Ding Y, Yao C, Lince-Faria M, Rath U, Cai W, Maiato H, Girton J, Johansen KM, Johansen J. Chromator is required for proper microtubule spindle formation and mitosis in Drosophila. Dev Biol. 2009 Oct 1;334(1):253-63.
11. Johansen KM, Cai W, Deng H, Bao X, Zhang W, Girton J, Johansen J. Polytene chromosome squash methods for studying transcription and epigenetic chromatin modification in Drosophila using antibodies. Methods. 2009 Aug;48(4):387-97.
12. Bao X, Cai W, Deng H, Zhang W, Krencik R, Girton J, Johansen J, Johansen KM. The COOH-terminal domain of the JIL-1 histone H3S10 kinase interacts with histone H3 and is required for correct targeting to chromatin. J Biol Chem. 2008 Nov 21;283(47):32741-50.
13. Cai W, Bao X, Deng H, Jin Y, Girton J, Johansen J, Johansen KM. RNA polymerase II-mediated transcription at active loci does not require histone H3S10 phosphorylation in Drosophila. Development. 2008 Sep;135(17):2917-25.
14. Deng H, Bao X, Cai W, Blacketer MJ, Belmont AS, Girton J, Johansen J, Johansen KM. Ectopic histone H3S10 phosphorylation causes chromatin structure remodeling in Drosophila. Development. 2008 Feb;135(4):699-705.

 

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