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http://www.webmedcentral.com/images/Header_Logo.giftext/html2011-07-22T17:46:40+01:00http://www.webmedcentral.com/Dr. Raghunath PrabhuChronic Calcific Pancreatitis with Concurrent Autoimmune Hemolytic Anemia: A Case Report
http://www.webmedcentral.com/article_view/1905
Chronic Pancreatitis is an irreversible inflammatory disease characterized by fibrosis and progressive destruction of exocrine and endocrine function. The common complications of chronic pancreatitis include bile duct obstruction with cholestasis, duodenal obstruction, portal/splenic vein hypertension, pancreatic pseudocysts, pancreatic fistula, ascites and rare complications like colonic stenosis.1 Autoimmune Hemolytic Anemia is an immune malfunction caused by autoantibodies which react with RBCs. It is further classified according to the temperature at which the autoantibodies react with the RBCs into warm antibody hemolytic anemia (>37° C) or cold agglutinin disease (. 2 3 4 Autoimmune Hemolytic Anemia has variable etiologies and can occur as a primary disorder where the cause cannot be determined or secondary to other autoimmune disorders such as systemic lupus erythematosus, various drugs, infections and hematological malignancies.5. Herein we report one rare case of a patient with chronic calcific pancreatitis with pseudocyst with concurrent autoimmune hemolytic anemia.text/html2012-05-07T16:22:31+01:00http://www.webmedcentral.com/Mr. Muhammed R SiddiquiThe Role of Calcium and Pro-Inflammatory Mediators in Acute Pancreatitis
http://www.webmedcentral.com/article_view/3337
Acute pancreatitis is a common condition that is potentially fatal in severe cases. Pancreatic acinar cell injury in acute pancreatitis results in inflammation. This causes a variety of systemic complications including organ damage, fat necrosis and vascular damage. Many aetiological factors responsible for causing acute pancreatitis have been identified. But the exact mechanisms through which they cause acute pancreatitis remain unclear. With increasing incidence rates of acute pancreatitis over the years and the lack of a definitive treatment, it is important that research continues in order to find successful treatment. This review analyses available literature in order to find the role of calcium and pro-inflammatory mediators in acute pancreatitis.