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Other Comments:
interesting report
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Competing interests:
none
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Invited by the author to review this article? :
No -
Have you previously published on this or a similar topic?:
No
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References:
None -
Experience and credentials in the specific area of science:
none
- How to cite: Bourgeois M .Gohil review[Review of the article 'Sanguinarine, Hydroxybutyrate Dehydrogenase and Fatigue in Epidemic Dropsy: A Retrospective Study of an Outbreak and its Control from Gujarat, India ' by Amin B].WebmedCentral 2014;3(5):WMCRW001831
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Other Comments:
Title of the article can be changed to "Clinical profile of Epidemic dropsy patients". Type of study has not been mentioned. A case definition could have been included. Place of estimation of HBDH and sanguinarine has not been mentioned. Authors should concentrate only on the clinical profile of epidemic dropsy patients. There are so many references at the end, however all are not used in the text.
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Competing interests:
No
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Invited by the author to review this article? :
No -
Have you previously published on this or a similar topic?:
No
-
References:
None -
Experience and credentials in the specific area of science:
I am mainly involved in the field of Public health research.
- How to cite: Verma P B.Sanguinarine, Hydroxybutyrate Dehadrogenase and Fatigue in Epidemic Dropsy: A retrospective study of a n outbreak and its control from Gujarat, India.[Review of the article 'Sanguinarine, Hydroxybutyrate Dehydrogenase and Fatigue in Epidemic Dropsy: A Retrospective Study of an Outbreak and its Control from Gujarat, India ' by Amin B].WebmedCentral 2014;3(3):WMCRW001539
It is a retrospective study [mentioned in title].
Estimation of HBDH and sanguinarine were done at Toxicology laboratory [ICMR], Lucknow, UP, India.
Reference 13-15 are mentioned with table 3 cardiac manifestations.
Case definition: Epidemic dropsy is a clinical state resulting from consumption of edible oils adulterated with Argemone Mexicana seed oil [due to toxin sanguinarine or dihydrosanguinarine].
Responded by Prof. Jayendra R Gohil on 03 Mar 2014 06:04:07 AM
This manuscript describes the Sanguinarine, Hydroxybutyrate Dehydrogenase and Fatigue in Epidemic Dropsy. It is interesting.
It is novel?
Yes
The results support the claims?
No
The methodology is valid?
The authors should add what supportive measures and antioxidants had been used.
Yes
No.
None
Yes
No
None
I had studied the similar topic.
Anti-oxidants were Vitamin C & E.
Supportive measures were admission, avoidance of the said oil; B complex vitamines and treatment of fever and anemia.
Responded by Prof. Jayendra R Gohil on 03 Mar 2014 05:55:59 AM