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What are the main claims of the paper and how important are they?
A differential diagnosis of angiofibroma should be considered for any patient coming with complaints of nasal mass and spontaneous, recurrent epistaxis irrespective of age, sex, site of origin and extension of the mass.An unusual tumour in a middle aged female, in an unusual site. These features are unusual as typically angiofibromas are found in boys in their teens, and it is nasopharyngeal in location.
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Are these claims novel? If not, please specify papers that weaken the claims to the originality of this one.
Though it is unusual, there are some artilces available similar to this case.
Yucel Akbas, Yucel Anadolu. Extranasopharyngeal angiofibroma of the head and neck in women. American Journal of Otolaryngology Volume 24, Issue 6, November–December 2003, Pages 413–416.
I Tasca and G Ceroni Compadretti. Extranasopharyngeal angiofibroma of nasal septum. A controversial entity. Acta Otorhinolaryngologica Italica. December 2008; 28(6):312-314.
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Are the claims properly placed in the context of the previous literature?
Yes, however, there are some more artcles relevant to this case report, like:
Yucel Akbas, Yucel Anadolu. Extranasopharyngeal angiofibroma of the head and neck in women. American Journal of Otolaryngology Volume 24, Issue 6, November–December 2003, Pages 413–416.
I Tasca and G Ceroni Compadretti. Extranasopharyngeal angiofibroma of nasal septum. A controversial entity. Acta Otorhinolaryngologica Italica. December 2008; 28(6):312-314.
K.K Handa, Abhinit Kumar, M.K. Singh, Aru H. Chhabra. Extranasopharyngeal angiofibroma arising from the nasal septum.International Journal of Pediatric Otorhinolaryngology Volume 58, Issue 2, 27 April 2001, Pages 163–166.
Robert Y Huang, Edward J Damrose, Keith E Blackwell, Alen N Cohen, Thomas C Calcaterra. Extranasopharyngeal Angiofibroma. International Journal of Pediatric Otorhinolaryngology. Volume 56, Issue 1, 30 November 2000, Pages 59–64.
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Do the results support the claims? If not, what other evidence is required?
Yes, it does.
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If a protocol is provided, for example for a randomized controlled trial, are there any important deviations from it? If so, have the authors explained adequately why the deviations occurred?
NA
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Is the methodology valid? Does the paper offer enough details of its methodology that its experiments or its analyses could be reproduced?
NA
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Would any other experiments or additional information improve the paper? How much better would the paper be if this extra work was done, and how difficult would such work be to do, or to provide?
NA
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Is this paper outstanding in its discipline? (For example, would you like to see this work presented in a seminar at your hospital or university? Do you feel these results need to be incorporated in your next general lecture on the subject?) If yes, what makes it outstanding? If not, why not?
This diagnosis should be considered in anyone, irrespective of age or sex, with nasal obstruction and epistaxis. Hence a good reminder to all clinicians.
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Other Comments:
An unusual presentation of angiofibroma, worth keeping in mind as a differential diagnosis in any patient with nasal obstruction and epistaxis.
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Competing interests:
None
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Invited by the author to review this article? :
No -
Have you previously published on this or a similar topic?:
No
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References:
No
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Experience and credentials in the specific area of science:
I have adequate experience in this clinical condition.
- How to cite: Mathew J .Nasal Angiofibroma - A Rare Presentation[Review of the article 'Nasal Angiofibroma - A Rare Presentation ' by Shah P].WebmedCentral 2013;4(7):WMCRW002801
Histopathology based diagnosis with CT findings support
Yes
Yes
Immunohisto chemisry might have been added.
Doesnot arise
Yes
Immuno histochemistry could have been done
Not necessarily
Many cases have been reported as bleeding polypus of the nasal septum
To call it i n terms nasopharyngel angiofibroma, there is no mention about torrential bleeding
only 15 to 20 ml
Number of episodes of epis taxis is not clear
Is there any periodicity, being female, though age is against
None
No
No
None
working in the fielod of rhinology for the past 25 years and has handled both Naso pharyngeal angiofibroma as well as bleeding polypus of the nasal septum One case thought as bleeding polypus has been diagnsoed as adenoid cystic carcinoma of the nasal septum.