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Submited on: 15 May 2012 11:15:11 AM GMT
Published on: 16 May 2012 06:39:46 PM GMT
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What are the main claims of the paper and how important are they?
The aim of this paper was to examine the range in the normal size of the third ventricle in a population of individuals living in North India
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Are these claims novel? If not, please specify papers that weaken the claims to the originality of this one.
Yes
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Are the claims properly placed in the context of the previous literature?
Yes
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Do the results support the claims? If not, what other evidence is required?
Yes
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If a protocol is provided, for example for a randomized controlled trial, are there any important deviations from it? If so, have the authors explained adequately why the deviations occurred?
No
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Is the methodology valid? Does the paper offer enough details of its methodology that its experiments or its analyses could be reproduced?
Yes
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Would any other experiments or additional information improve the paper? How much better would the paper be if this extra work was done, and how difficult would such work be to do, or to provide?
No
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Is this paper outstanding in its discipline? (For example, would you like to see this work presented in a seminar at your hospital or university? Do you feel these results need to be incorporated in your next general lecture on the subject?) If yes, what makes it outstanding? If not, why not?
Yes- it would make for a great seminar in a university or hospital
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Other Comments:
The researchers conclude that the morphopometric parameters of the third ventricle, when studied by MRI in a population in North India, showed antero-posterior length is statistically significant from 6-30 years. They also state that the width anterior to the interthalmic adhesion has no statistical significance.
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Competing interests:
No
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Invited by the author to review this article? :
No -
Have you previously published on this or a similar topic?:
No
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References:
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Experience and credentials in the specific area of science:
Clinical Associate Professor
- How to cite: Maloney W J.Assessment of Third Ventricle with MRI in a Population in North India[Review of the article 'Assessment of Third Ventricle with MRI: Morphological Variations Among Different Gender and Age Group ' by Bakshi S].WebmedCentral 2012;3(7):WMCRW002118
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I have read the manuscript entitled “Assessment of Third Ventricle with MRI: Morphological Variations Among Different Gender and Age Group”and recommend that it should be minor revision with a few changes. Detailed MRI protocol and statistical analysis are required. Two examples are shown at ''any other comments''.
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Detailed MRI protocol and statistical analysis are required. Two examples are shown at ''any other comments''.
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Two examples for detailed MRI protocol and statistical analysis are shown following:
For detailed MRI protocol;
All patients were examined by 1.5 Tesla superconducting MR scanner (The New Intera Nova, Philips Medical Systems, Best, The Netherlands) using a standard quadrature head coil with version 9 software release. The system was equipped with magnetic field gradients capable of a maximum strength of 33 mT/m and maximum slew rate of 160 T/m/s. Axial and sagittal T1 weighted (583/15 ms, TR/TE, one excitation) spin-echo images were obtained by using 5 mm slice thickness with a 1 mm intersection gap, 220x220 mm field of view (FOV) and 256x256 matrix size.
For detailed statistical analysis;
MS-Excel 2003 and SPSS for Win. Ver. 15.00 (SPSS Inc., Chicago, IL., USA) and NCSS 2007 (Hintze J. (2006), NCSS, PASS, and GESS. NCSS, Kaysville, Utah, USA) software were used for statistical analysis. Distribution of variables was checked graphically and using the Shapiro-Wilk test. Descriptive statistics related to the variables are given as mean±standard deviation. Independent Sample t test (student's t test) was used for parametric variables and Mann-Whitney U test was used for non-parametric variables. For making comparisons according to age groups, ANOVA test was used for parametric variables and Bonferroni post-hoc test was used for defining the source of difference. For non-parametric variables Kruskal-Wallis variance analysis was used and Bonferroni corrected Mann-Whitney U test was used for defining the source of difference. The relationship between age groups and r2 was analyzed using Pearson correlation and the relationship between age groups and L was analyzed using Spearman's (Rho) rank correlation. p?0.05 was set as significant.
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Anatomy