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Submited on: 02 Oct 2010 06:59:57 AM GMT
Published on: 02 Oct 2010 07:35:34 PM GMT
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Other Comments:
Nice worth reading article
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Competing interests:
no
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Invited by the author to review this article? :
Yes -
Have you previously published on this or a similar topic?:
No
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References:
None -
Experience and credentials in the specific area of science:
Experience in immunology
- How to cite: Parkash O .Antiinflammatory, Antimicrobial And Immunomodulatory Properties Of Lactobacillus Casei Against Enteropathogenic Escherichia Coli [Review of the article 'Antiinflammatory, antimicrobial and immunomodulatory properties of Lactobacillus casei against Enteropathogenic Escherichia coli ' by Kumar A].WebmedCentral 2012;1(11):WMCRW00132
- Other Comments: The work is seems to be nice and informative. Because,this article indicated many benefits of oral administration of L. casei against pathogenic E. coli. It has mentioned that the wistar rats administered with L. casei shown increased hemoglobin, better liver functions, anti-inflammatory and Immunomodulatory property against enteropathogenic E. coli. Conclude, gastrointestinal tract immunity against enteropathogenic E. coli may be generated by using L. casei (either live or dead) as a food or vaccine through oral route.
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Competing interests:
No
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Invited by the author to review this article? :
Yes -
Have you previously published on this or a similar topic?:
No
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References:
None -
Experience and credentials in the specific area of science:
Previous experience in Microbiology, Immunology, Biochemistry (areas of Life science). Presently I am working against viral diseases which are mainly affecting in Central Part of India. - How to cite: Deval H .Oral administration of L. casei as an immunomodulator against pathogenic E. coli[Review of the article 'Antiinflammatory, antimicrobial and immunomodulatory properties of Lactobacillus casei against Enteropathogenic Escherichia coli ' by Kumar A].WebmedCentral 2012;1(11):WMCRW00115
- Other Comments: NICE WORK SHOWING PROPERTIES OF PROBIOTICS
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Competing interests:
NO
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Invited by the author to review this article? :
No -
Have you previously published on this or a similar topic?:
Yes
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References:
None -
Experience and credentials in the specific area of science:
ALREADY WORKING ON THE IMMUNOMODULATION OF PROBIOTICS - How to cite: Singh V N.ORAL VACCINE AGINST INFECTIOUS TRAUMAS[Review of the article 'Antiinflammatory, antimicrobial and immunomodulatory properties of Lactobacillus casei against Enteropathogenic Escherichia coli ' by Kumar A].WebmedCentral 2012;1(10):WMCRW0050
The main claim of this article is that Lactobacillus casei can be used to protect animals from enteropathogenic Escherichia coli infection.
This claim, although not surprising, is indeed novel.
Yes.
The results, although very poorly presented, do support the claim.
Not applicable.
Yes. My only comment with regards to this is that the fact that animals received daily doses of L. casei should be more clearly indicated in the "Experimental schedule" section. This is clearly stated in the abstract, but not in the main body of the paper.
No.
This paper is certainly not outstanding. It is very poorly written and the subject itself is not groundbreaking. Although the research is novel and interesting, the fact that administration of L. casei protects against an enteric pathogen is highly intuitive and expected.
As I mentioned above, this paper would benefit enormously from a revision of grammar, word choice, and sentence structure. The language used is so poor that sometimes it is difficult to understand the scientific concepts and reasoning presented.
None
No
No
Over 15 years of experience in microbiology research.