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What are the main claims of the paper and how important are they?
Acute bilateral simultaneous posterior ischaemic optic neuropathy (PION) developed after. Such cases have r normal vaginal delivery is a very rare occurrence.
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Are these claims novel? If not, please specify papers that weaken the claims to the originality of this one.
No because there was post partum hemorrhage.
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Are the claims properly placed in the context of the previous literature?
Yes
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Do the results support the claims? If not, what other evidence is required?
Fundus photograph, fundus angiography, MRI of the orbit and brain should be provided for readers to judge that all investigations were indeed normal.
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If a protocol is provided, for example for a randomized controlled trial, are there any important deviations from it? If so, have the authors explained adequately why the deviations occurred?
Not applicable
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Is the methodology valid? Does the paper offer enough details of its methodology that its experiments or its analyses could be reproduced?
Not applicable
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Would any other experiments or additional information improve the paper? How much better would the paper be if this extra work was done, and how difficult would such work be to do, or to provide?
Not applicable
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Is this paper outstanding in its discipline? (For example, would you like to see this work presented in a seminar at your hospital or university? Do you feel these results need to be incorporated in your next general lecture on the subject?) If yes, what makes it outstanding? If not, why not?
Yes if the authors can provide fundus photograph, fundus angiography, MRI of the orbit and brain and ERG of the patient.
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Other Comments:
The authors should discuss the role of iv methylprednisolone in the treatment of PION
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Competing interests:
Nil
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Invited by the author to review this article? :
No -
Have you previously published on this or a similar topic?:
No
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References:
None -
Experience and credentials in the specific area of science:
Clinical experience
- How to cite: Anonymous.Posterior Ischaemic Optic Neuropathy Following Vaginal Delivery [Review of the article 'Posterior Ischaemic Optic Neuropathy Following Vaginal Delivery ' by Puri M].WebmedCentral 2012;3(6):WMCRW001957
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Other Comments:
Suggest adding some more references in the introduction section. Especially where you cite that 30% of post haemorrhagic amaurosis is the result of uterine haemorrhage.
Was IV contrast given for the MRI?
Was a HVF or GVF performed? Was there a VF defect?
Was color vision testing performed?
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Competing interests:
No
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Invited by the author to review this article? :
No -
Have you previously published on this or a similar topic?:
No
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References:
None -
Experience and credentials in the specific area of science:
I'm a practicing ophthalmologist.
- How to cite: Leng T .PION Following Vaginal Delivery[Review of the article 'Posterior Ischaemic Optic Neuropathy Following Vaginal Delivery ' by Puri M].WebmedCentral 2012;3(4):WMCRW001741
Sudden hypotension complicated with anaemia can lead to acute bilateral simultaneous posterior ischaemic optic neuropathy (PION) post partum vaginal delivery.
Yes
Yes
Yes
Not Applicable
Not Applicable
Please Include IOP Values
Not Applicable
No
No
No
Yes
ACS67, a hydrogen sulphide-releasing derivative of latanoprost acid, attenuates retinal ischemia and oxidative stress to RGC-5 cells in culture. Invest Ophthalmol Vis Sci. 2009 Aug 26;
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