Submited on: 26 Apr 2012 12:43:59 PM GMT
Published on: 26 Apr 2012 03:00:42 PM GMT
 

1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    Complete loss of vision in patients with pre eclampsia and eclampsia is a rare occurance and therefore presents scientific interest for ophthalmologists as  well as ginecologist. However , the mechanisms of this syndrom remain to be obscure. I didn't find author's efforts to investigate caual relations between retina and central parts of the brain. The paper demonstrates only fact without any mechanisms and explanations. 

  • Competing interests:
    No
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    I am retina biochemist

  • How to cite:  Shukolyukov A.Reversible Blindness in Severe Pre eclampsia[Review of the article 'Reversible Blindness in Severe Pre eclampsia ' by Puri M].WebmedCentral 2012;3(5):WMCRW001790
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Review of Article
Posted by Dr. Theodore Leng on 26 Apr 2012 09:41:57 PM GMT

1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    This is a very intersting report of vision loss in the setting of pre-eclampsia.

     

    The case report is confusing in that it states nifedepine was used to control BP initially, and then later on states that "antihypertensives were administered."  One can only assume that post-delivery, no BP meds were given.  This should be clarified.


    It would be good to note if IV contrast was used for the CT scan and to state why a MRI with gad wasn't performed instead (not available?).  The discussion should be lengthened to discuss what "hypodense" lesions in the occipital lobe imply.


    Was an afferent pupillary defect present in either eye?


    There was some evidence of retinal vascular involvement per the case report, so 1) it would be incorrect to state that "Cortical blindness is a clinical syndrome characterized by intact pupillary reflexes and normal fundoscopic findings" because there were fundoscopic findings in this case and 2) a fluorescein angiogram would have helped in the diagnosis to determine if vascular compromise or stasis was the cause of the vision loss.  Profound non-perfusion in the both eyes/optic nerves could have caused this patient's visual symptoms as well.

  • Competing interests:
    No
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    I am a retina specialist.

  • How to cite:  Leng T .Review of Article[Review of the article 'Reversible Blindness in Severe Pre eclampsia ' by Puri M].WebmedCentral 2012;3(4):WMCRW001738
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