Submited on: 22 Mar 2012 09:21:43 AM GMT
Published on: 22 Mar 2012 04:07:36 PM GMT
 
Role of CT in Colonic Cancer
Posted by Dr. Shyamsunder R Koteyar on 04 Feb 2013 02:33:01 PM GMT

  • What are the main claims of the paper and how important are they?

    The article has been nicely written, to demonstrate the role of CT imaging in colonic cancer. This article demonstrates the need of preopertaive imaging in mangement of colonic cancer.


  • Are these claims novel? If not, please specify papers that weaken the claims to the originality of this one.

    There have been sveral articles on this topic, for example,
    http://radiographics.rsna.org/content/20/2/419.long

    However, this article once again emphasizes the role of CT.


  • Are the claims properly placed in the context of the previous literature?

    Yes


  • Do the results support the claims? If not, what other evidence is required?

    Yes


  • If a protocol is provided, for example for a randomized controlled trial, are there any important deviations from it? If so, have the authors explained adequately why the deviations occurred?

    Yes


  • Is the methodology valid? Does the paper offer enough details of its methodology that its experiments or its analyses could be reproduced?

    Yes, although a larger study would have been more helpful.


  • Would any other experiments or additional information improve the paper? How much better would the paper be if this extra work was done, and how difficult would such work be to do, or to provide?

    No


  • Is this paper outstanding in its discipline? (For example, would you like to see this work presented in a seminar at your hospital or university? Do you feel these results need to be incorporated in your next general lecture on the subject?) If yes, what makes it outstanding? If not, why not?

    It is a good paper, written in clear simple language. The afact laid out in this article has also been proven on mulitple papaers previously.


  • Other Comments:

    Nicely written article. Good demonstration with relavent images.

     

    The sample size used( 50 patients with proven colonic cancer) is very small, and a much larger sample size would have definatley added value.

     

    The article does not cover those cases which were diagnosed on CT, but missed on colonoscopy.

  • Competing interests:
    None
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    I am radiologist with about 18 years expereince in abdominal imaging.

  • How to cite:  Koteyar S R.Role of CT in Colonic Cancer[Review of the article 'Computed Tomography Interpretation in Colonic Cancer: Let there be more Exhaustive ' by Vezzelli E].WebmedCentral 2012;4(2):WMCRW002484
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    The article was written in satisfactory way. Actually  volumetric CT has achieved  a fundamental role in planning  surgical tractament of colonrectal cancer.

    The limit of CT is a low specifity for linfonodal involment in order to distinguish between normal-reactive lynfonodes and metastatic lynfonodes.

    The capability to discern the tumor grading through contrast enhancement is interesting, of course the specificity of this is quite high, but not optimal.

    Intersting the correlation with persitent enhancement of peri-tumoral prominent veins and angio-invasion of the tumor.

    Volumetric CT actually has a fundamental role in preoperative staging.

    The article gives usefull surgical indications for radiology interpretation.

     

     

  • Competing interests:
    No
  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    Yes
  • References:
    3-T MRI with phased-array surface coil in the local staging of rectal cancer. Radiol. Medica (2011) 116:375-388 (ed. springer)
  • Experience and credentials in the specific area of science:

    Abdominal Radiologist with expirience in MRI and CT

  • How to cite:  Sani F .Computed Tomography Interpretation in Colonic: Let there be more Exhaustive[Review of the article 'Computed Tomography Interpretation in Colonic Cancer: Let there be more Exhaustive ' by Vezzelli E].WebmedCentral 2012;3(4):WMCRW001653
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