Submited on: 30 Aug 2011 11:58:17 AM GMT
Published on: 31 Aug 2011 11:24:45 AM GMT
 

1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

     

       The author makes an interesting point of distinguishing the genotoxic effects caused by 

    solid-phase fibers themselves from the effect caused by the chemical substances that are attached to

    these nano-structures. The common genotixins are polycyclic-aromatic molecules, e.g. aromatic amines

    that form strong covalent bonds to DNA causing generic mutations during replication. In fact, ny nucleophilic compound would potentially represent a genotoxic risk. 

     

    It seems that the authors atributes more significance to the chemicals that adhere to the nano-particles

    than the the paticles themselves in causing the genotoxic effects, which sounds reasonable.

     

    I would suggest replacing "Mud particles did not cause genotoxicity in contrast to soil contaminated aromatics."

    by "Mud particles did not cause genotoxicity in contrast to soil containing the contaminated aromatics".

     

    Can the author list what paticular aromatic molecules have been observed?

     

  • Competing interests:
    No
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    Carbon nano-structures.

  • How to cite:  Bytautas L .Solid-phase Environmental Genotoxicity: In Vivo Veritas![Review of the article 'Solid-phase Environmental Genotoxicity: In Vivo Veritas! ' by Varga C].WebmedCentral 2012;3(1):WMCRW001433
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Accept completely
Posted by Prof. Amir Jalali on 08 Nov 2011 03:25:54 PM GMT

1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Partly
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? No
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

     

    Dear the WebmedCentral Team,

     

    The article was checked well. The article has both scientific and interesting sounds. It was well organized as a short communication. The presented data were based on logical evidences. As well the article was well written. Therefore this article is scope of interest for all public health holders and toxicology researchers. 

     

    With regards,

     

    Prof Amir Jalali,

    Dept of Pharmacology and Toxicology,

    School of Pharmacy, Jundishapur University,

    Ahvaz, Iran.  

     

  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    I got invovlved in this area from the past year. My publications will be published soon.

  • How to cite:  Jalali A .Accept completely [Review of the article 'Solid-phase Environmental Genotoxicity: In Vivo Veritas! ' by Varga C].WebmedCentral 2012;2(11):WMCRW001107
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